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1.
Cureus ; 15(10): e47951, 2023 Oct.
Article in English | MEDLINE | ID: mdl-38034263

ABSTRACT

Hypertensive disorders of pregnancy, particularly preeclampsia, are significant contributors to maternal and fetal mortality worldwide. HELLP (hemolysis, elevated liver enzymes, and low platelet count) syndrome constitutes a severe manifestation of preeclampsia. Subcapsular liver hematoma (SLH) is a rare complication of HELLP syndrome, resulting from blood accumulation between the liver parenchyma and the Glisson's capsule. We present a unique case of a pregnant patient with HELLP syndrome complicated by SLH, leading to gastric outlet obstruction (GOO). The patient's medical history, clinical presentation, diagnostic evaluation, and management are discussed. The patient, with a history of pregnancy-induced hypertension, presented with HELLP syndrome at 34 weeks of gestation. Elevated blood pressure, liver enzymes, and low platelet count were observed. Postpartum, the patient developed SLH causing GOO. Conservative management, including intravenous fluids, pain control, and a nasogastric tube, was employed. Imaging confirmed SLH and GOO. Multidisciplinary collaboration guided the treatment approach, emphasizing close monitoring, nonoperative strategies, and dietary adjustments. The patient's condition improved, and she was discharged on postpartum day 20. This case report underscores the challenges of managing HELLP syndrome complications, especially SLH-induced GOO. Early diagnosis, appropriate medical interventions, and interdisciplinary coordination are pivotal in ensuring positive outcomes. Conservative management can be effective in stable patients, but timely recognition and monitoring remain crucial for averting potential complications. This case contributes to the limited literature on managing such complex scenarios and highlights the importance of tailored strategies in multifaceted medical conditions.

2.
Cureus ; 14(8): e27923, 2022 Aug.
Article in English | MEDLINE | ID: mdl-36110487

ABSTRACT

Neuroleptic malignant syndrome (NMS) has been defined as a life-threatening neurologic emergency related to the use of antipsychotic medications. It is most often seen with high-potency (first-generation) antipsychotic medications and may occur after a single dose. There have been conflicting reports in the literature of an atypical NMS (ANMS) presentation, associated with lower-potency agents (second generation) antipsychotic medications. NMS is usually diagnosed with a tetrad of clinical symptoms although none of the tetrads is needed for diagnosis. We report a case of a patient admitted for severe acute syndrome coronavirus 2 (SARS-CoV2) pneumonia who developed probable ANMS. SARS-CoV2 also referred to as coronavirus disease 2019 (COVID-19) added another dimension of complication to patient care as we have, at this time, an incomplete understanding of the pathogenesis. We feel critical care clinicians should maintain broad differentials to clinical findings, during the use of multiple medications and not simply attribute the various presentations to COVID-19.

3.
Ochsner J ; 18(2): 183-187, 2018.
Article in English | MEDLINE | ID: mdl-30258303

ABSTRACT

BACKGROUND: A massive pulmonary embolism (PE) is associated with high mortality once cardiac arrest occurs. Surgical embolectomy is indicated in patients who have massive PE. CASE REPORT: A 62-year-old male emergently underwent surgical embolectomy after sustaining an intraoperative cardiac arrest caused by a massive PE during an open reduction with internal fixation of a closed comminuted midshaft tibia fracture. Postoperatively, the patient developed pulmonary hypertension and acute renal failure. He was treated with aerosolized epoprostenol for right ventricular strain secondary to pulmonary hypertension. He survived the hospital course and was discharged without any other major complications. CONCLUSION: Surgical embolectomy is a viable option for massive PE, and aerosolized epoprostenol can be used as adjuvant treatment for right ventricular strain secondary to acute pulmonary hypertension.

4.
Ann Card Anaesth ; 20(4): 459-461, 2017.
Article in English | MEDLINE | ID: mdl-28994687

ABSTRACT

A patient presented for an elective transcatheter aortic valve replacement with temporary transvenous pacing (TVP) wires placement per protocol. On postoperative day 1, the patient remained stable, so the wires were subsequently removed, after which the patient acutely decompensated, with transthoracic echocardiography revealing pericardial effusion. Emergent pericardiocentesis was performed, and a pericardial drain was placed. Three days later, the drain was removed; again, the patient acutely decompensated, requiring another emergent pericardiocentesis. Despite the relatively benign nature of TVP wires and pericardial drains, the possibility of cardiac tamponade should be kept in mind as a potential complication when they are being removed.


Subject(s)
Cardiac Tamponade/etiology , Device Removal/adverse effects , Drainage/adverse effects , Intraoperative Complications/therapy , Pacemaker, Artificial/adverse effects , Aged , Cardiac Tamponade/diagnostic imaging , Echocardiography , Electrodes , Female , Humans , Intraoperative Complications/diagnostic imaging , Pericardial Effusion/etiology , Pericardial Effusion/therapy , Pericardiocentesis , Pericardium
5.
Antimicrob Agents Chemother ; 56(5): 2756-8, 2012 May.
Article in English | MEDLINE | ID: mdl-22314536

ABSTRACT

A high rate of broad-spectrum-ß-lactamase-producing Escherichia coli isolates was identified from seagull and pelican feces collected in the Miami Beach, Florida, area. The most commonly identified resistance determinants were CMY-2 and CTX-M-15. Those wild birds might be therefore considered vehicles for wide dissemination of multidrug-resistant Enterobacteriaceae in the United States.


Subject(s)
Bird Diseases/microbiology , DNA, Bacterial/analysis , Escherichia coli Infections/veterinary , Escherichia coli/genetics , beta-Lactamases/genetics , Animals , Base Sequence , Birds , Disease Reservoirs , Escherichia coli/isolation & purification , Escherichia coli/pathogenicity , Escherichia coli Infections/microbiology , Feces/microbiology , Florida , Microbial Sensitivity Tests , Molecular Sequence Data , Plasmids/genetics , beta-Lactam Resistance/genetics
6.
Infect Control Hosp Epidemiol ; 31(10): 1074-7, 2010 Oct.
Article in English | MEDLINE | ID: mdl-20738186

ABSTRACT

We describe the investigation and control of a Klebsiella pneumoniae carbapenemase-producing K. pneumoniae outbreak in a 20-bed surgical intensive care unit during the period from January 1, 2009 through January 1, 2010. Nine patients were either colonized or infected with a monoclonal strain of K. pneumoniae. The implementation of a bundle of interventions on July 2009 successfully controlled the further horizontal spread of this organism.


Subject(s)
Anti-Bacterial Agents/therapeutic use , Bacterial Proteins/biosynthesis , Critical Care , Disease Outbreaks/prevention & control , Infection Control/methods , Klebsiella Infections/drug therapy , Klebsiella pneumoniae/drug effects , beta-Lactamases/biosynthesis , Anti-Bacterial Agents/pharmacology , Bacterial Proteins/genetics , Female , Florida/epidemiology , Hospitals, Teaching , Humans , Klebsiella Infections/epidemiology , Klebsiella Infections/microbiology , Klebsiella pneumoniae/enzymology , Klebsiella pneumoniae/genetics , Klebsiella pneumoniae/isolation & purification , Male , Microbial Sensitivity Tests , Middle Aged , Treatment Outcome , beta-Lactamases/genetics
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