ABSTRACT
Hemophilia B is a recessive hereditary disease, and manifestations result from coagulation factor IX deficiency. Although improbable, as factor IX is produced exclusively in the liver, the possibility of developing the disease after transplantation represents an infrequent but potentially morbid complication. Standard laboratory tests may be insufficient to determine the probability of transmission of this pathology. This report describes the case of a patient who developed hemophilia B after liver transplantation whose donor had no prior knowledge of the disease.
ABSTRACT
Lemierre syndrome is a rare complication of oropharyngeal infection, especially acute pharyngotonsillitis, associated with septicemia and thrombophlebitis of the internal jugular vein (IJV). We present the case of a 52-year-old patient who underwent liver transplantation and returned with symptoms of pain, redness and left cervical bulging 1 month after surgery. After investigation, the diagnosis of septic thrombophlebitis of the IJV was made. The patient responded well to treatment with antibiotic therapy and full anticoagulation. To the best of our knowledge, the present report is the first report of Lemierre syndrome in a post-liver transplant patient.
Subject(s)
Lemierre Syndrome , Sepsis , Thrombophlebitis , Anti-Bacterial Agents/therapeutic use , Humans , Immunocompromised Host , Jugular Veins/diagnostic imaging , Lemierre Syndrome/complications , Lemierre Syndrome/diagnosis , Lemierre Syndrome/surgery , Middle Aged , Sepsis/complications , Sepsis/etiology , Thrombophlebitis/diagnostic imaging , Thrombophlebitis/drug therapyABSTRACT
Introdução: Expansão tecidual é um método de reconstrução importante para a cobertura de defeitos como queimaduras e nevos gigantes ou na reconstrução mamária. Esse artigo tem como objetivo relatar a experiência do Serviço de Cirurgia Plástica do Hospital de Clínicas da Universidade Federal do Paraná (UFPR) com o uso de expansores. Métodos: Esse é um estudo retrospectivo, descritivo e analítico dos pacientes que foram submetidos à expansão tecidual para cirurgia reconstrutora no Hospital de Clínicas da UFPR, entre o período de janeiro de 2010 a dezembro de 2016. Resultados: Foram analisados 61 pacientes e 80 cirurgias, incluindo os procedimentos de reexpansão. A idade variou entre 2 a 73 anos (média 31). A grande maioria dos pacientes pertenceu ao sexo feminino (83,6%), na faixa etária acima de 40 anos, sendo submetidos ao tratamento para reconstrução mamária após mastectomia radical (36%). As complicações observadas nesses pacientes foram: sinais de infecção (14,7%), deiscência da sutura (3,2%), seroma (3,2%), defeito no expansor (3,2%), exposição do expansor (3,2%), necrose (1,6%) e sinais de hipoperfusão (1,6%). Pacientes submetidos à reconstrução mamária tiveram o maior número de complicações (40,1%). A reexpansão foi necessária em 37,7% dos pacientes. Conclusão: A técnica de expansão de pele é indicada para o tratamento de diversas patologias. O procedimento de expansão tecidual apresenta taxas de complicações altas e o conhecimento do perfil do paciente, dos principais tipos de complicações e dos fatores associados a essas complicações podem auxiliar na sua prevenção.
Introduction: Tissue expansion is an important reconstruction method to solve defects such as burns and giant nevi or breast reconstruction. This article aims to report the experience of the Plastic Surgery Service of the Hospital de Clínicas of the Federal University of Paraná (UFPR) with the use of expanders. Methods: This is a retrospective, descriptive, and analytical study of patients who underwent tissue expansion for reconstructive surgery at the Hospital de Clínicas da UFPR, from January 2010 to December 2016. Results: 61 patients and 80 surgeries were analyzed, including re-expansion procedures. Age ranged from 2 to 73 years (mean 31). The majority of patients were female (83.6%), aged over 40 years, undergoing breast reconstruction treatment after radical mastectomy (36%). The complications observed in these patients were: signs of infection (14.7%), suture dehiscence (3.2%), seroma (3.2%), defect in the expander (3.2%), exposure of the expander (3, 2%), necrosis (1.6%) and signs of hypoperfusion (1.6%). Patients undergoing breast reconstruction had the highest number of complications (40.1%). Reexpansion was necessary for 37.7% of patients. Conclusion: The skin expansion technique is indicated for several pathologies' treatment. The tissue expansion procedure has high complication rates. Knowing the patient's profile, the main types of complications, and the factors associated with these complications can help prevent them.
