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1.
Appl Radiat Isot ; 156: 108991, 2020 Feb.
Article in English | MEDLINE | ID: mdl-32056686

ABSTRACT

The 106Ru/106Rh COB-type plaque has a cut-out section that makes it suitable to be used in eye brachytherapy to treat tumours close to the optical nerve. Nevertheless, this asymmetry makes measurements and calculations of dose rates around this kind of beta applicator more difficult to perform. In this work we present a analytical and numerical method to evaluate the relative dose rates along the central axis of the COB-type plaque and a comparison is made with a result found in literature obtained by means of Monte Carlo simulation.


Subject(s)
Brachytherapy/methods , Eye Neoplasms/radiotherapy , Radiotherapy Dosage , Rhodium/chemistry , Ruthenium/chemistry , Humans , Monte Carlo Method
2.
Bioresour Technol ; 193: 337-44, 2015 Oct.
Article in English | MEDLINE | ID: mdl-26143001

ABSTRACT

In this work, esterification of fatty acids (oleic, linoleic and stearic acid) with a commercial zinc carboxylate (a layered compound formed by simultaneous intercalation of stearate and palmitate anions) was performed. Kinetic modeling using a quasi-homogeneous approach successfully fitted experimental data at different molar ratio of fatty acids/alcohols (1-butanol and 1-hexanol) and temperature. An apparent first-order reaction related to all reactants was found and activation energy of 66 kJ/mol was reported. The catalyst showed to be unique, as it can be easily recovered like a heterogeneous catalysts behaving like ionic liquids. In addition, this catalyst demonstrated a peculiar behavior, because higher reactivity was observed with the increase in the alcohols chain length compared to the authors' previous work using ethanol.


Subject(s)
1-Butanol/pharmacology , Fatty Acids/metabolism , Hexanols/pharmacology , Palmitates/pharmacology , Stearic Acids/pharmacology , Biocatalysis/drug effects , Bioreactors , Esterification/drug effects , Kinetics , Models, Theoretical , Oleic Acid/pharmacology , Reproducibility of Results , Temperature
3.
J Appl Clin Med Phys ; 13(1): 3671, 2012 Jan 05.
Article in English | MEDLINE | ID: mdl-22231219

ABSTRACT

The skyshine radiation phenomenon consists of the scattering of primary photon beams in the atmosphere above the roof of a medical linear accelerator facility, generating an additional dose at ground level in the vicinity of the treatment room. Thus, with respect to radioprotection, this situation plays an important role when the roof is designed with little shielding and there are buildings next to the radiotherapy treatment room. In literature, there are few reported skyshine-measured doses and these contain poor agreement with empirical calculations. In this work, we carried out measurements of skyshine photon dose rates produced from eight different 6 and 10 MV medical accelerators. Each measurement was performed outside the room facility, with the beam positioned in the upward direction, at a horizontal distance from the target and for a 40 cm × 40 cm maximum photon field size at the accelerator isocenter. Measured dose-equivalent rates results were compared with calculations obtained by an empirical expression, and differences between them deviated in one or more order of magnitude.


Subject(s)
Occupational Exposure/analysis , Particle Accelerators , Photons , Radiation Dosage , Radiation Monitoring/methods , Radiation Protection/methods , Equipment Failure Analysis , Scattering, Radiation
4.
J Appl Clin Med Phys ; 12(2): 3330, 2011 Jan 30.
Article in English | MEDLINE | ID: mdl-21587175

ABSTRACT

The Brazilian Institute of Radiation Protection and Dosimetry (IRD/CNEN) carried out quality assurance regulatory audits in Brazilian radiotherapy facilities from 1995 to 2007. In this work, the set of data collected from 195 radiotherapy facilities that use high-energy photon beams are analyzed. They include results from audits in linear electron accelerators and/or Co-60 units. The inspectors of IRD/CNEN performed the dosimetry of high-energy radiotherapy photon beams according to the IAEA dosimetry protocols TRS 277 and TRS 398, and the values of measurements were compared to stated values. Other aspects of radiological protection were checked during on-site audits such as calibration certification of clinical dosimeters and portable monitors, existence and use of check source, use of barometer and thermometer, individual dose registry and training of staff. It was verified that no check source was available in 38% of the visited facilities; the training of personnel was not adequate in 9% of the facilities and the registry of accumulated individual doses was not being done in 6% of the facilities. Measurements of absorbed dose have indicated deviations in the range ± 3% for 67.6% of the cobalt-60 units and 79.6% of medical linear accelerators; 18.5% of Co-60 irradiators and 9.6% of linear accelerators presented deviations in the range 3% < δ ≤ 5%. Finally, 13.9% of Co-60 facilities and 10.8% of linear accelerator facilities presented dosimetry deviations above 5%. The effort in dosimetric quality control performed by IRD/CNEN audits has yielded positive changes that make radiation treatment facilities more reliable.


Subject(s)
Radiometry/methods , Radiotherapy, High-Energy/methods , Brazil , Calibration , Cobalt Isotopes/chemistry , Humans , Particle Accelerators , Quality Control , Radiation Oncology/standards , Radiation Protection/methods , Radiotherapy Dosage , Radiotherapy, High-Energy/standards , Safety , Thermometers
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