ABSTRACT
This article describes a modification of the double-osteotomy radial technique that has been described previously and summarizes our clinical experience with this method in 4 female patients. All patients had improvement in functional motion and were satisfied with the improved appearance of their wrist after surgery.
Subject(s)
Growth Disorders/surgery , Osteotomy/methods , Radius/abnormalities , Radius/surgery , Trapezoid Bone/transplantation , Adolescent , Adult , Bone Plates , Bone Transplantation/methods , Female , Humans , Patient Satisfaction , Radiography , Radius/diagnostic imaging , Radius/growth & development , Range of Motion, Articular , Treatment Outcome , Wrist Joint/abnormalities , Wrist Joint/diagnostic imaging , Wrist Joint/growth & development , Wrist Joint/surgeryABSTRACT
OBJECTIVE: The aim of this study is to compare the effects of traditional nonsteroidal anti-inflammatory drugs with nonsteroidal anti-inflammatory drugs that are selective cyclooxygenase-2 (COX-2) inhibitors in the process of bone regeneration in a rat model. MATERIALS AND METHODS: Forty-four Wistar strain rats were subjected to osteotomy of the right femur and randomly divided into 3 groups according to the drug to be given (diclofenac, rofecoxib, or placebo). Each group was divided into 2 subgroups according to the time to euthanasia after the surgery. The animals of Subgroup 1 were submitted to euthanasia 2 weeks after surgery, and those of Subgroup 2, underwent euthanasia 4 weeks after surgery. Radiographic examinations and bone callus histomorphometry were analyzed. RESULTS: No intergroup statistical difference was found in the bone callus area or in bone formation area 2 and 4 weeks after surgery. Intra-group analysis concerning the bone neoformation area inside the callus showed a significant difference within the diclofenac group, which presented less tissue. CONCLUSIONS: Fracture consolidation in Wistar rats occurs within less than 2 weeks, and the use of nonsteroidal anti-inflammatory drugs does not significantly influence this process.
Subject(s)
Anti-Inflammatory Agents, Non-Steroidal/pharmacology , Bone Regeneration/drug effects , Bony Callus/surgery , Cyclooxygenase 2 Inhibitors/pharmacology , Diclofenac/pharmacology , Lactones/pharmacology , Sulfones/pharmacology , Animals , Bony Callus/diagnostic imaging , Bony Callus/pathology , Osteotomy , Radiography , Rats , Rats, Wistar , Time FactorsABSTRACT
Os autores analisam casuística de 11 pacientes vítimas de amputaçöes ao nível do polegar provocadas por mecanismo de avulsäo. Relatam as técnicas das reconstruçöes realizadas e referem os resultados obtidos, imediatamente e tardios. A maioria das amputaçöes ocorreu ao nível da articulaçäo metacarpofalangiana. O índice de sucesso em termos de sobrevida e resultado funcional satisfatório foi de 64 por cento. Concluem que, mesmo nestas situaçöes de alta complexidade, os reimplantes do polegar sempre devem ser realizados
