ABSTRACT
Cholestatic jaundice is a well-known complication of gram-negative bacterial infections in the neonates. Newborn and premature infants are particularly vulnerable to cholestasis because of immaturities in bile forming mechanisms. The Authors describe two premature infants who developed cholestasis in the course of a proved bacterial infection by Klebsiella pneumoniae. The main clinical aspects of this association are illustrated and the recent concepts of pathogenetic mechanism of intrahepatic cholestasis is discussed.
Subject(s)
Cholestasis/complications , Infant, Premature, Diseases/etiology , Klebsiella Infections/etiology , Klebsiella pneumoniae , Female , Humans , Infant, Newborn , MaleABSTRACT
A case of solitary hepatic abscess in an apparently normal 5-year old infant is described. The symptoms in this patient were generally nonspecific and the child were erroneously operated with a presumptive diagnosis of acute appendicitis. Subsequently, because of persistence of isolated abdominal signs, abdominal ultrasonography were performed, and an abscess of the right hepatic lobe was evidenced. The pathogenesis of the hepatic abscess in this child is unclear.
Subject(s)
Liver Abscess/diagnosis , Acute Disease , Aminoglycosides/therapeutic use , Ampicillin/therapeutic use , Appendicitis/diagnosis , Child , Diagnosis, Differential , Humans , Liver Abscess/diagnostic imaging , Liver Abscess/drug therapy , Male , UltrasonographyABSTRACT
A case of acute thrombocytopenic purpura complicating live measles vaccination is reported. Clinically and morphologically this case is identical to the postinfectious thrombocytopenic purpura. An immunological mechanism has been postulated to explain the thrombocytopenia.
Subject(s)
Measles Vaccine/adverse effects , Purpura, Thrombocytopenic/etiology , Child, Preschool , Female , Humans , Prognosis , Purpura, Thrombocytopenic/diagnosisABSTRACT
Goltz syndrome or focal dermal hypoplasia is a hereditary disorder, is a rare mesodermal hypoplasia found primarily in females. It is characterized by linear hypoplasia of the skin and tumors of fat or lipomatous lesions. There are significant defects of the skeleton, dental structures, eyes, soft tissues and skin. In our work an example of new-born female with this syndrome is reported, and a review of 136 cases from the literature is presented.
