Subject(s)
Endoscopy, Digestive System/methods , Incidental Findings , Stomach Diseases/pathology , Xanthomatosis/pathology , Biopsy, Needle , Female , Follow-Up Studies , Humans , Immunohistochemistry , Lung Neoplasms/diagnosis , Lung Neoplasms/therapy , Lymphoma, B-Cell/diagnosis , Lymphoma, B-Cell/therapy , Middle Aged , Neoplasm Staging , Risk Assessment , Severity of Illness Index , Stomach Diseases/diagnosis , Xanthomatosis/diagnosisABSTRACT
The association between gastric carcinoma and lymphoma is rare. Confocal laser endomicroscopy is a new diagnostic tool that allows the identification of cellular and vascular architecture during endoscopy. This is the first report of an in vivo early gastric carcinoma diagnosis by confocal laser endomicroscopy in a patient successfully treated for a primary gastric diffuse large-B-cell lymphoma.
Subject(s)
Adenocarcinoma/diagnosis , Endoscopy, Digestive System/methods , Lymphoma, Large B-Cell, Diffuse/diagnosis , Microscopy, Confocal/methods , Neoplasms, Second Primary/diagnosis , Stomach Neoplasms/diagnosis , Adenocarcinoma/drug therapy , Adenocarcinoma/pathology , Adenocarcinoma/surgery , Antineoplastic Combined Chemotherapy Protocols , Combined Modality Therapy , Early Detection of Cancer , Gastrectomy , Humans , Lymphoma, Large B-Cell, Diffuse/drug therapy , Lymphoma, Large B-Cell, Diffuse/surgery , Male , Middle Aged , Neoplasms, Second Primary/drug therapy , Neoplasms, Second Primary/pathology , Neoplasms, Second Primary/surgery , Stomach/pathology , Stomach Neoplasms/drug therapy , Stomach Neoplasms/pathology , Stomach Neoplasms/surgeryABSTRACT
Anterior resection of the rectum is a frequent surgical procedure. However, abnormal bowel habits following this procedure are frequently reported. The functional evaluation of these patients is usually limited to the anorectal area. By means of colonic manometry, we have evaluated a patient with frequent urge for defecation and increased bowel frequency following anterior resection of the rectum with straight coloanal anastomosis and almost normal anorectal function. Analysis of the tracing revealed a reduction of contractile segmental activity and much more high-amplitude propagated contractions than which occur in healthy subjects. These high-amplitude propagated contractions, representing the manometric equivalent of mass movements, were always in association with urge for defecation and, sometimes, with loose stools. High-amplitude simultaneous contractions were also observed. We feel that the surgical resection of a potential physiological brake may be responsible for these observations.
Subject(s)
Colon/physiopathology , Rectal Neoplasms/surgery , Rectum/surgery , Aged , Humans , Male , Manometry/methods , Postoperative Care , Postoperative ComplicationsABSTRACT
Selective serotonin reuptake inhibitors are frequently employed to treat depression. However, although rarely, coagulation abnormalities have been described following the use of these compounds, and these effects appear to be enhanced by simultaneous use of nonsteroidal anti-inflammatory drugs. We describe a case of reversible symptomatic duodenal compression caused by a retroperitoneal hematoma after ingestion of sertraline and nimesulide.
Subject(s)
Anti-Inflammatory Agents, Non-Steroidal/adverse effects , Duodenal Diseases/etiology , Hematoma/chemically induced , Intestinal Obstruction/etiology , Retroperitoneal Space/diagnostic imaging , Selective Serotonin Reuptake Inhibitors/adverse effects , Sertraline/adverse effects , Sulfonamides/adverse effects , Depression/drug therapy , Drug Interactions , Duodenal Diseases/diagnostic imaging , Female , Hematoma/complications , Hematoma/diagnostic imaging , Humans , Intestinal Obstruction/diagnostic imaging , Middle Aged , Selective Serotonin Reuptake Inhibitors/therapeutic use , Sertraline/therapeutic use , Tomography, X-Ray ComputedABSTRACT
Chronic constipation is one of the more frequent functional gastrointestinal symptoms. The more severe cases not infrequently undergo a major surgical approach. However, there is still a need for a better diagnostic and therapeutic approach, since the results are still unpredictable, probably due to a poor selection of candidates. This article focuses on the current diagnostic approach to chronic constipation, with an emphasis on the possible role of colonic manometry to help better choose those patients that may benefit from surgery.
