[The role of galactography in the diagnosis of breast diseases. Our experience]. / Il ruolo della galattografia nella diagnostica senologica. Nostra esperienza.

Following a description of the most common galactographic semeiotics in relation to the different types of secretion, the Authors report their personal experience in the use of galactography to diagnose breast cancer. Histopathological tests revealed the presence of carcinoma in 14 (29.2%) out of a total 48 galactographic examinations. In conclusion, the Authors underline the high degree of diagnostic precision of galactography, a test which contributes to the identification of a considerable number of carcinomas during the preclinical stage.

[The value of the triad: clinical examination, mammography and needle aspiration cytology in the diagnosis of breast carcinoma. Our experience]. / Validità della tripletta: esame clinico, mammografia e citologia per agoaspirazione nella diagnosi del carcinoma della mammella. Nostra esperienza.

Based on the authors' personal experience of the use of the triad, clinical examination, mammography and needle-aspiration cytology, in the strategic diagnosis of breast cancer, the paper emphasizes the importance of early diagnosis as the sole means of obtaining an improved outcome. Using this integrated methodology the authors have obtained a specificity of 99%, sensitivity of 97.8%, and a diagnostic accuracy and prognostic value for positive tests of 98%. In conclusion, the authors affirm that the comparative interpretation of clinical examination, mammography and cytology appears to be an extremely efficacious and reliable method for the diagnosis of the nature of breast nodules.

[Biological effects of ultrasonics used in diagnosis. Experimental studies on the incorporation of tritiated thymidine into rat hepatocytes]. / Effetti biologici degli ultrasuoni impiegati a scopo diagnostico. Ricerche sperimentali sull'incorporazione di timidina tritiata in epatociti di ratto.

In order to evaluate the possible effects of diagnostically employed ultrasounds on DNA turnover, 35 Wistar strain rats were subjected to an ultrasonic frequency band of 2.25 MHz for exposure times varying from 10 to 500 seconds. Upon administration of thymidine tritiate, it was observed that capacity to absorb the substance remained largely normal in those rats exposed for up to 40 seconds, but was diminished where longer exposure times were employed.

[Dosimetry "in vivo" with thermoluminescent detectors. 2. Results of the use of 99mTc-sulfocolloid in radioisotope diagnosis of the liver]. / Dosimetria "in vivo" con rivelatori a termoluminescenza Nota 2. Risultati per impiego di 99mTc-solfocolloidale nella radioisotopodiagnostica del fegato.

Absorbed does values detected by thermoluminescence-type minidosimeters implanted in vivo in the dog following the diagnostic administration of 99mTc-sulphocolloid are reported. They are compared with those obtained when colloid 198Au was used in the same way, and with the mathematically calculated data reported in the literature.

[Dosimetry in hepato-biliary "in vivo" with thermoluminescent detectors. 3. Results of the use of I 131-rose bengal radioisotope diagnosis]. / Dosimetria "in vivo" con rivelatori a termoluminescenza Nota 3. Risultati per implego di [3]I-rosa bengala nella radioisotopodiagnostica epato-biliare.

Absorbed dose values measured in certain dog organs by in vivo application of RTL minidosimeters followed by i.v. adminstration of rose begal 131I in doses employed on a routine basis in hepatobiliary isotopodiagnosis are reported. The results are compared with those reported in the literature, obtained with a mathematical method.

[Histoenzymatic studies and internal irradiation. III. Histoenzymatic changes of the kidney treated with chloromeridrin Hg 197]. / Ricerche istoenzimatiche ed irradiazione interna. III) Modificazioni istoenzimatiche del rene di ratto trattato con cloromeridrin Hg 197

The histochemical behaviour of alkaline phosphatase, adenosintriphosphatase, acid phosphatase and acetylglucosaminidase activities was studied in rat kidney treated with Chloromeridrin Hg. In these experimental conditions it was found that the nephrocytes in the proximal convoluted tubule present changes in the enzymatic activities examined, generally proportional to the doses employed. With lower doses of radionuclides, the histoenzymatic changes have a local character and are completely reversible after a month. With higher doses they take on a more extensive character and persis to some extent one month after treatment. These findings suggesti that Hg could be used clinically with due precautions.