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Diabetes Metab ; 30(3): 276-9, 2004 06.
Article in English | MEDLINE | ID: mdl-15223980

ABSTRACT

Non-islet cell tumor-related hypoglycemia is a rare phenomenon. We report the case of a 63 Year-old man admitted for hemiparesia and a capillary blood glucose of 20 mg/dL. The presence of an immature form of IGF-II that can mimic the effect of insulin, namely "big IGF-II", explained this patient's hypoglycaemia. A moderately differentiated adenocarcinoma of the cardia with metastatic extension to the stomach and the liver was demonstrated. Octreotide failed to control the hypoglycaemia, therefore prednisolone (2 mg/kg per day) and enteral feeding prevented new episodes of severe hypoglycaemia.


Subject(s)
Adenocarcinoma/diagnosis , Blood Glucose/metabolism , Hypoglycemia/etiology , Insulin-Like Growth Factor II/physiology , Stomach Neoplasms/diagnosis , Fatal Outcome , Humans , Male , Middle Aged , Octreotide/therapeutic use
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