[Interchangeability of the fat-to-fat-free mass ratios obtained by means arm anthropometric measures, skinfold thickness, and bioelectrical impedance]. / Grado de acuerdo entre los índices adiposo-musculares obtenidos a partir de medidas antropométricas del brazo, pliegues cutáneos e impedancia bioeléctrica.

BACKGROUND: Body fat, fat free mass and the relationship between both, the fat-to-fat-free mass ratio are useful parameters in the nutritional evaluation of the patient. The aim of this study is to evaluate the degree of agreement among the fat-to-fat-free mass ratios obtained by arm anthropometric measures (fat-muscle index, FMI), Siri equation for the sum of four skinfold thickness (body fat-muscle index, BFMISiri) and triceps skinfold (BFMItriceps) and bioelectrical impedance (BFMIOmron) methods. METHODS: This is a cross-sectional study. A total of 145 patients were evaluated by anthropometry and bioelectrical impedance (Omron BF 300), being estimated the agreement through the Intraclass Correlation Coefficient (ICC) and Bland-Altman method. The reference method was BFMISiri. RESULTS: The ICC between BFMISiri-BFMItriceps were 0.9304 (0.9035; 0.9498), between BFMISiri-FMI of 0.7726 (0.6846; 0.8361) and between BFMISiri-BFMIOmron of 0.9114 (0.8771; 0.9361). BFMItriceps (limits of agreement -0.171 to 0.117) show the best agreement according to Bland-Altman analysis with BFMISiri, followed by BMFISiri-BFMIOmron (-0.186; 0.178). The agreement limits between FMI and BFMISiri (-0.2; 0.42), BFMItriceps (-0.26; 0.42) or BFMIOmron (-0.292; 0.504) were beyond of the established cut-off points (-0.2; 0.2). CONCLUSIONS: Due to the nature of the statistical agreement BFMItriceps and BFMIOmron are methods interchangeable methods between them and with BFMISiri. FMI is not interchangeable with BFMISiri, BFMIOmron or BFMItriceps. These results suggest that FMI cannot estimate properly the body composition. BFMItriceps and BFMIOmron are valid alternative methods to be used instead BFMISiri in the fat-to-fat-free mass ratio assessment.

[Validation of the OMRON BF 300 monitor for measuring body fat by bioelectric impedance]. / Validación del monitor de medición de la grasa corporal por impedancia bioeléctrica OMRON BF 300.

OBJECTIVES: To assess the accuracy of the OMRON BF 300 body fat monitor using bioelectric impedance and to validate its measurement of body fat percentage (BF%) against the Siri equation. DESIGN: Cross-sectional descriptive study. SETTING: Primary care. Coronel de Palma and San Fernando Health Centres, Móstoles. PARTICIPANTS: 88 people took part in the assessment of the accuracy of the monitor, and 91 in the validation. MEASUREMENTS AND MAIN RESULTS: The BF% were recorded in triplicate, with the mean being the figure noted. Precision was evaluated through the intra-class correlation coefficient (ICC) and the coefficient of variation (CV); validity, through technical error, the ICC and the Bland-Altman method. In the Siri equation, body density was calculated through the Durnin-Womersley equation. Precision: ICC was 0.999 and CV 0.4 +/- 0.03. VALIDATION: the difference between the BF% monitor (26.6 +/- 9.1%) and the Siri equation (27.8 +/- 8.2%) was -1.27% (p < 0.01; 95% CI -1.97 to -0.57); the technical error of the monitor was 2.2% and of the ICC 0.956 (95% CI, 0.9335-0.9710). Thus, 80.2% of the monitor-equation differences were below 5%, with a concordance interval under the Bland-Altman method of +5.45 to -7.99%. CONCLUSIONS: The OMRON BF 300 monitor satisfies the precision criteria (ICC > 0.95 and low CV) and validation (excellent technical error, ICC > 0.75 and clinically acceptable differences) and is a valid alternative to cutaneous folds as a method of assessing nutrition of the patient.

[Multicenter clinical, double blind, and randomized study to assess the effectiveness and safety of binifibrate versus gemfibrozil in type IIa, IIb, and IV hyperlipidemia]. / Estudio clínico multicéntrico, doble ciego y randomizado para valorar la eficacia y tolerancia de binifibrato versus gemfibrozil en hiperlipidemias tipo IIa, IIb y IV.

A multicentric, double-blind and randomized clinical study was conducted on a total of 54 patients with hyperlipidemias type IIa, IIb and IV in order to compare the effectivity and tolerance of two hyperlipemiant drugs: Binifibrate and Gemfibrozil. The treatment had a length of six months, performing clinical and analytical controls at: baseline, 1 month, 2 months, 4 months and 6 months. Both drugs showed a very good tolerance and the following results were obtained: Total cholesterol: Binifibrate -21.9%, Gemfibrozil -20.5%; Triglycerides: Binifibrate -48.6%, Gemfibrozil -43.27%; HDL: Binifibrate +18.2%, Gemfibrozil -12.8%; LDL: Binifibrate -24.3%, Gemfibrozil -22.8% VLDL: Binifibrate -48%, Gemfibrozil -43.2%; Apo A: Binifibrate +133.5%, Gemfibrozil +108.1%; Apo B: Binifibrate -59.7%, Gemfibrozil -46%. Both treatment were very effective, although the greater increase produced by Binifibrate on Chol-HDL, with a statistically significant difference versus the increase produced by Gemfibrozil, must be highlighted.

Effect of povidone iodine and chlorhexidine on the mortality and bacterial clearance in the abdominal cavity of peritonitis rats.

Peritonitis was induced in Wistar rats by intraperitoneal inoculation of pure Escherichia coli. The mortality rate in the untreated control group was 36% (18/50). Rats in which 2 ml 1% povidone iodine had been injected intraperitoneally 5 min after the bacterial challenge, had a significantly increased mortality rate (43/50, 86%) (p less than 0.01). When the same experiment was done with 2 ml of 0.05% chlorhexidine the mortality rate decreased significantly to 16% (8/50) (p less than 0.05). Povidone iodine did not have any bactericidal effect; on the contrary, the number of colonies of bacteria had increased in all the animals 12 and 24 hours after challenge. Chlorhexidine, on the other hand, had sufficient bactericidal effect to cause a progressive decrease in the concentration of intraperitoneal bacteria.

[Adult T-cell lymphoblastic lymphoma associated with quiescent multiple myeloma]. / Linfoma linfoblástico T del adulto asociado a mieloma múltiple quiescente.

We report the case history of a female patient suffering of a T lymphoblastic lymphoma with an atypical presentation and evolution, consisting of pleuropericardiac effusion without mediastinic masses that coexists with a plasma cell dyscrasia that fulfils the criteria for stationary multiple myeloma. The possible pathogenic relationship between both processes is discussed, emphasizing the functional evolutive dissociation between the cellular constituents of both neoplasias, immature T lymphoblasts and plasma cells, respectively; this constitutes the first reported case in literature.