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Linkage of a pedigree drawing program and database to a program for determining BRCA mutation carrier probability.
Sand, Sharon R; DeRam, David S; MacDonald, Deborah J; Blazer, Kathleen R; Weitzel, Jeffrey N.
Fam Cancer ; 4(4): 313-6, 2005.
Article in English | MEDLINE | ID: mdl-16341809

ABSTRACT

An export module was developed for transferring primary relational pedigree data directly from a widely used pedigree program and relational database to the BRCAPRO program for calculation of BRCA gene mutation probability estimation.


Subject(s)
Genetic Testing/methods , Heterozygote , Neoplasms/genetics , Probability , Software , Tumor Suppressor Proteins/genetics , Adolescent , Adult , Child , Databases, Genetic , Female , Genetic Predisposition to Disease , Humans , Male , Middle Aged , Mutation , Pedigree , Predictive Value of Tests , Risk Factors , Sensitivity and Specificity
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