Liquid-crystal-based visible-light integrated optical phased arrays and application to underwater communications.

In this Letter, we present the first, to the best of our knowledge, liquid-crystal-based integrated optical phased arrays (OPAs) that enable visible-light beam forming and steering. A cascaded OPA architecture is developed and experimentally shown to emit a beam in the far field at a 632.8-nm wavelength with a power full width at half maximum of 0.4°×1.6° and 7.2° beam-steering range within ±3.4 V. Furthermore, we show the first visible-light integrated-OPA-based free-space-optical-communications transmitter and use it to demonstrate the first integrated-OPA-based underwater-wireless-optical-communications link. We experimentally demonstrate a 1-Gbps on-off-keying link through water and an electronically-switchable point-to-multipoint link with channel selectivity greater than 19 dB through a water-filled tank.

Cost of long-distance energy transmission by different carriers.

This paper compares the relative cost of long-distance, large-scale energy transmission by electricity, gaseous, and liquid carriers (e-fuels). The results indicate that the cost of electrical transmission per delivered MWh can be up to eight times higher than for hydrogen pipelines, about eleven times higher than for natural gas pipelines, and twenty to fifty times higher than for liquid fuels pipelines. These differences generally hold for shorter distances as well. The higher cost of electrical transmission is primarily because of lower carrying capacity (MW per line) of electrical transmission lines compared to the energy carrying capacity of the pipelines for gaseous and liquid fuels. The differences in the cost of transmission are important but often unrecognized and should be considered as a significant cost component in the analysis of various renewable energy production, distribution, and utilization scenarios.

The use of disfluency cues in spoken language processing: Insights from aging.

Past research suggests listeners treat disfluencies as informative cues during spoken language processing. For example, studies have shown that child and younger adult listeners use filled pauses to rapidly anticipate discourse-new objects. The present study explores whether older adults show a similar pattern, or if this ability is reduced in light of age-related declines in language and cognitive abilities. The study also examines whether the processing of disfluencies differs depending on the talker's age. Stereotyped ideas about older adults' speech could lead listeners to treat disfluencies as uninformative, similar to the way in which listeners react to disfluencies produced by non-native speakers or individuals with a cognitive disorder. Experiment 1 used eye tracking to capture younger and older listeners' real-time reactions to filled pauses produced by younger and older talkers. On critical trials, participants followed fluent or disfluent instructions referring to either discourse-given or discourse-new objects. Younger and older listeners treated filled pauses produced by both younger and older talkers as cues for reference to discourse-new objects despite holding stereotypes regarding older adults' speech. Experiment 2 further explored listeners' biased judgments of talkers' fluency, using auditory materials from Experiment 1. Speech produced by an older talker was rated as more disfluent and slower than a younger talker even though these features were matched across recordings. Together, the findings demonstrate (a) older listeners' effective use of disfluency cues in real-time processing and (b) that listeners treat both older and younger talkers' disfluencies as informative despite biased perceptions regarding older talkers' speech. (PsycInfo Database Record (c) 2021 APA, all rights reserved).

High prevalence of dysfibrinogenemia among patients with chronic thromboembolic pulmonary hypertension.

The mechanism by which chronic thromboembolic pulmonary hypertension (CTEPH) develops after acute pulmonary thromboembolism is unknown. We previously reported that fibrin from CTEPH patients is relatively resistant to fibrinolysis in vitro. In the present study, we performed proteomic, genomic, and functional studies on fibrin(ogen) to investigate whether abnormal fibrin(ogen) might contribute to the pathogenesis of CTEPH. Reduced and denatured fibrinogen from 33 CTEPH patients was subjected to liquid chromatography-mass spectrometry analysis. Fibrinogen from 21 healthy controls was used to distinguish atypical from commonly occurring mass peaks. Atypical peaks were further investigated by targeted genomic DNA sequencing. Five fibrinogen variants with corresponding heterozygous gene mutations (dysfibrinogenemias) were observed in 5 of 33 CTEPH patients: Bbeta P235L/gamma R375W, Bbeta P235L/gamma Y114H, Bbeta P235L, Aalpha L69H, and Aalpha R554H (fibrinogens(San Diego I-V)). Bbeta P235L was found in 3 unrelated CTEPH patients. Functional analysis disclosed abnormalities in fibrin polymer structure and/or lysis with all CTEPH-associated mutations. These results suggest that, in some patients, differences in the molecular structure of fibrin may be implicated in the development of CTEPH after acute thromboembolism.