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1.
A new naturally occurring erythromycin: erythromycin F.
Martin, J R; DeVault, R L; Sinclair, A C; Stanaszek, R S; Johnson, P.
J Antibiot (Tokyo) ; 35(4): 426-30, 1982 Apr.
Article in English | MEDLINE | ID: mdl-7096198

Subject(s)
Erythromycin/isolation & purification , Magnetic Resonance Spectroscopy , Mass Spectrometry , Streptomyces/metabolism
2.
A new antibiotic XK-62-2. III The structure of XK-62-2, a new gentamicin C complex antibiotic.
Egan, R S; DeVault, R L; Mueller, S L; Levenberg, M I; Sinclair, A C; Stanaszek, R S.
J Antibiot (Tokyo) ; 28(1): 29-34, 1975 Jan.
Article in English | MEDLINE | ID: mdl-1126866

ABSTRACT

The structure of XK-62-2 has been firmly established to be 6'-N-methylgentamicin C1a (3) by application of spectroscopic methods in conjunction with chemical degradation. The data obtained in every case are completely consistent with the proposed structure.


Subject(s)
Gentamicins , Chemical Phenomena , Chemistry , Chromatography, Thin Layer , Mass Spectrometry , Methylation
3.
A novel class of diketopiperazines.
DeVault, R L; Rosenbrook, W.
J Antibiot (Tokyo) ; 26(9): 532-4, 1973 Sep.
Article in English | MEDLINE | ID: mdl-4792065

Subject(s)
Anti-Bacterial Agents/isolation & purification , Piperazines/isolation & purification , Animals , Anti-Bacterial Agents/pharmacology , Antifungal Agents/isolation & purification , Antifungal Agents/pharmacology , Arthrodermataceae/drug effects , Bacteria/drug effects , Benzyl Compounds/isolation & purification , Benzyl Compounds/pharmacology , Chemical Phenomena , Chemistry , Disulfides/isolation & purification , Disulfides/pharmacology , Magnetic Resonance Spectroscopy , Mice , Protons , Sulfides/isolation & purification , Sulfides/pharmacology
4.
Semisynthetic coumermycins. II. Preparation and properties of 3-(substituted benzamido)-4-hydroxy-8-methyl-7-[3-O-(5-methyl-2-pyrrolylcarbonyl)noviosyloxy] coumarins.
Schmitz, H; DeVault, R L; McDonnell, C D; Godfrey, J C.
J Antibiot (Tokyo) ; 21(10): 603-10, 1968 Oct.
Article in English | MEDLINE | ID: mdl-5715670

Subject(s)
Anti-Bacterial Agents/chemical synthesis , Coumarins/chemical synthesis , Anti-Bacterial Agents/pharmacology , Chemical Phenomena , Chemistry , Coumarins/pharmacology , In Vitro Techniques , Infrared Rays , Klebsiella/drug effects , Magnetic Resonance Spectroscopy , Methods , Pseudomonas/drug effects , Spectrum Analysis , Staphylococcus/drug effects , Streptococcus/drug effects , Ultraviolet Rays
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