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J Med ; 13(4): 303-7, 1982.
Article in English | MEDLINE | ID: mdl-6957529

ABSTRACT

We assessed the presence of bone and bone marrow involvement in seven men with advanced carcinoma of the prostate. The routine methods of history-taking, skeletal radiography, and radionuclide bone scans were supplemented by bone marrow aspiration, bone marrow biopsy, and performance of cytogenetic studies upon the aspirated bone marrow, without culture in vitro. Only radiology, bone scan, and marrow biopsy possessed adequate sensitivity. Definite cytogenetic abnormalities (45, XO) were found in two patients but the chromosome studies did not increase the rate of detection of marrow involvement by tumor.


Subject(s)
Bone Marrow/pathology , Bone Neoplasms/diagnosis , Prostatic Neoplasms/diagnostic imaging , Aged , Biopsy , Bone Neoplasms/diagnostic imaging , Bone Neoplasms/secondary , Bone and Bones/diagnostic imaging , Cell Transformation, Neoplastic/pathology , Humans , Karyotyping , Male , Prostatic Neoplasms/genetics , Prostatic Neoplasms/pathology , Radiography , Radionuclide Imaging
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