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Nanoscale ; 6(4): 2073-6, 2014 Feb 21.
Article in English | MEDLINE | ID: mdl-24424277

ABSTRACT

Small molecules can be co-loaded with iron oxide nanoparticles onto diatoms. With an external magnetic field, the diatoms, after systemic administration, can be attracted to tumors. This study suggests a great potential of diatoms as a novel and powerful therapeutic vehicle.


Subject(s)
Diatoms/chemistry , Drug Delivery Systems/methods , Ferric Compounds , Magnetic Fields , Nanoparticles/chemistry , Neoplasms, Experimental/drug therapy , Animals , Ferric Compounds/chemistry , Ferric Compounds/pharmacology , Mice , Neoplasms, Experimental/pathology
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