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Bioorg Med Chem Lett ; 9(2): 209-12, 1999 Jan 18.
Article in English | MEDLINE | ID: mdl-10021930

ABSTRACT

1,2,4-Oxadiazoles have been prepared in parallel using 1,1'-carbonyldiimidazole (CDI) as a reagent for both formation and cyclodehydration of O-acyl benzamidoximes. The use of CDI facilitates parallel purification of the oxadiazole products by simple liquid-liquid extraction and filtration.


Subject(s)
Imidazoles/chemistry , Oxadiazoles/chemical synthesis , Benzamidines/chemistry , Carboxylic Acids/chemistry , Oxadiazoles/isolation & purification
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