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Am J Med Sci ; 301(6): 395-7, 1991 Jun.
Article in English | MEDLINE | ID: mdl-2039026

ABSTRACT

Metastasis from basal cell carcinoma (BCC) of skin is rare. A case of a 58-year-old male presenting with increasing shortness of breath and right pleural effusion is described. Open right pleural biopsy demonstrated metastatic carcinoma consistent with BCC. Review of medical records from another hospital revealed that four years previously a recurrent BCC had been excised from the left back. One and three years prior to this excision, a skin lesion at this same site had been treated with electrocautery. Review of the skin excision slides demonstrated infiltrating BCC histologically very similar to the metastatic pleural neoplasm. The patient died two months after the pleural biopsy. At autopsy, the cutaneous BCC had not recurred and metastatic BCC extensively infiltrated the pleura bilaterally, with focal involvement of underlying lung parenchyma, subcarinal lymph nodes, diaphragm, and pericardium.


Subject(s)
Carcinoma, Basal Cell/pathology , Neoplasm Metastasis/pathology , Respiratory Insufficiency/etiology , Skin Neoplasms/pathology , Carcinoma, Basal Cell/diagnosis , Carcinoma, Basal Cell/drug therapy , Female , Fluorouracil/therapeutic use , Humans , Lung/pathology , Lung Neoplasms/pathology , Lung Neoplasms/secondary , Male , Middle Aged , Pleura/pathology , Pleural Effusion , Respiratory Insufficiency/pathology , Skin Neoplasms/diagnosis , Skin Neoplasms/drug therapy
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