ABSTRACT
Membranoproliferative glomerulonephritis is an uncommon condition that affects the glomeruli of the kidneys; its prevalence has decreased in our environment. Membranoproliferative glomerulonephritis has a characteristic histology that can be associated to different diseases. The clinical presentation varies, and to achieve a definitive diagnosis a renal biopsy must be done. Treatment is based on the underlying disease; when a drop in glomerular filtration rate is detected, immunosuppressants are prescribed. We describe the management of a 47-year-old female with membranoproliferative glomerulonephritis secondary to hepatitis C virus infection, a condition with very low prevalence.
Subject(s)
Glomerulonephritis, Membranoproliferative , Hepatitis C , Female , Humans , Middle Aged , Glomerulonephritis, Membranoproliferative/therapy , Glomerulonephritis, Membranoproliferative/complications , Hepacivirus , Hepatitis C/complications , Hepatitis C/diagnosis , Hepatitis C/drug therapy , Kidney/pathology , NephrectomyABSTRACT
Secretory carcinoma of the breast is a rare entity, characterized by the presence of intra- and extracellular, eosinophilic and acelular secretions. They are negative for hormone receptors and do not express human epidermal growth factor receptor HER-2/neu. However, the clinical outcome is favorable. Multicentricity is very unusual. We report a case of a 32-year-old woman with a multicentric secretory carcinoma of the breast. The main pathological features are discussed together with a review of the pertinent literature.
Subject(s)
Breast Neoplasms/pathology , Carcinoma/pathology , Neoplasms, Multiple Primary/pathology , Adult , Biopsy, Needle , Breast/pathology , Breast Neoplasms/chemistry , Breast Neoplasms/diagnostic imaging , Carcinoma/chemistry , Carcinoma/diagnostic imaging , Female , Humans , Neoplasms, Multiple Primary/chemistry , Neoplasms, Multiple Primary/diagnostic imagingABSTRACT
We performed a review of the epithelioid-type angiomas to determine their clinical course and propose an appropriate plan for follow-up. We present the case of a patient with possible adrenal carcinoma suggested by computed tomography for whom the histopathologic study revealed an epithelioid angiomyolipoma arising from the kidney. In the absence of consensus, we consider it worthwhile to register the very few cases diagnosed and record a detailed follow-up of the clinical course. We recommend surgical treatment and a follow-up regimen similar to that for renal carcinoma.
