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Fitoterapia ; 78(6): 426-9, 2007 Sep.
Article in English | MEDLINE | ID: mdl-17628348

ABSTRACT

The antiproliferative activity of fresh fruit juices extracted from Citrus sinensis (cv. Washington Navel and cv. Sanguinello), C. deliciosa cv. Avana, C. clementina cv. Nules, C. aurantium subsp. myrtifolia , was evaluated against K562 (human chronic myelogenous leukemia), HL-60 (human leukemia) and MCF-7 (human breast adenocarcinoma) cell lines. All the juices tested showed antiproliferative activity. Moreover, the pattern of the main flavanone compounds in the juices has been determined by HPLC analysis.


Subject(s)
Antineoplastic Agents, Phytogenic/pharmacology , Cell Proliferation/drug effects , Citrus , Phytotherapy , Antineoplastic Agents, Phytogenic/administration & dosage , Antineoplastic Agents, Phytogenic/therapeutic use , Cell Line, Tumor/drug effects , Chromatography, High Pressure Liquid , Flavanones/administration & dosage , Flavanones/chemistry , Flavanones/pharmacology , Flavanones/therapeutic use , Fruit , HL-60 Cells/drug effects , Humans , K562 Cells/drug effects
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