Effectiveness of 3 COVID-19 Vaccines in Preventing SARS-CoV-2 Infections, January-May 2021, Aragon, Spain.

Reducing severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) transmission is a worldwide challenge; widespread vaccination could be one strategy for control. We conducted a prospective, population-based cohort study of 964,258 residents of Aragon, Spain, during December 2020-May 2021. We used the Cox proportional-hazards model with vaccination status as the exposure condition to estimate the effectiveness of 3 coronavirus disease vaccines in preventing SARS-CoV-2 infection. Pfizer-BioNTech had 20.8% (95% CI 11.6%-29.0%) vaccine effectiveness (VE) against infection after 1 dose and 70.0% (95% CI 65.3%-74.1%) after 2 doses, Moderna had 52.8% (95% CI 30.7%-67.8%) VE after 1 dose and 70.3% (95% CI 52.2%-81.5%) after 2 doses, and Oxford-AstraZeneca had 40.3% (95% CI 31.8%-47.7%) VE after 1 dose. All estimates were lower than those from previous studies. Results imply that, although high vaccination coverage remains critical to protect people from disease, it will be difficult to effectively minimize transmission opportunities.

[Health assets and quality of life in people diagnosed with severe mental disorder]. / Activos para la salud y calidad de vida en personas diagnosticadas de enfermedad mental grave.

OBJECTIVE: To identify health assets and describe quality of life for people diagnosed with severe mental disorder through their own testimonies; to understand the necessities and barriers that affect their quality of life; and offer improvement recommendations. METHOD: A qualitative, descriptive analysis based on the information obtained through semi-structured interviews and asset mapping. RESULTS: Assets are similar to those found in undiagnosed people, while needs and barriers differ in both groups. The main assets include social relationships, socioeconomic assets, personal development, leisure and free time assets, places, art, daily activities, which usually take place within the mental health network, sense of belonging, and autonomy. To improve their health and life quality, they need access to employment and studies, more and better social relationships, and more control over their lives. Side effects of medication and socio-economic exclusion, and the lack of autonomy derived from it are the main existing barriers, which have a negative effect in self-esteem and social interactions. An important measure to improve health and quality of life is the increase of economic and social assets for a more autonomous personal development. CONCLUSIONS: This community action for health care has served to reveal the similarities between health and quality of life assets for severe mental disorder diagnosed and undiagnosed people, as well as the differences in the needs and difficulties to achieve them.