1.
C R Seances Soc Biol Fil
; 179(2): 276-82, 1985.
Article
in French
| MEDLINE
| ID: mdl-2990638
ABSTRACT
Human skin fibroblasts which are naturally resistant to Parvovirus H-1 can be lysed by this virus after SV40 transformation. This observation raises the possibility that oncosuppression by Parvovirus involves a direct oncolytic effect.
Subject(s)
Cell Transformation, Viral , Parvoviridae/pathogenicity , Simian virus 40/physiology , Viral Interference , Animals , Cell Division , Cells, Cultured , Fibroblasts/microbiology , Humans , Skin/microbiology
2.
C R Seances Soc Biol Fil
; 179(2): 283-9, 1985.
Article
in French
| MEDLINE
| ID: mdl-2990639
ABSTRACT
Parvovirus H-1 was used to probe the cellular radiosensitivity of two human degeneration syndromes AT and HC. No difference in the survival of gamma irradiated H-1 was detected between skin fibroblasts from such patients and from a normal individual. However, AT and normal cells were distinguished by the fact that the reactivation of irradiated H-1 could be increased by UV or X-irradiation of the latter but not of the former cells.