Subject(s)
Bile Acids and Salts/blood , Liver Diseases/blood , Adolescent , Adult , Chronic Disease , Fasting , Female , Food , Hepatitis/blood , Humans , Liver Cirrhosis/blood , Male , Middle AgedSubject(s)
Bile Acids and Salts/blood , Liver Diseases/diagnosis , Adult , Aged , Eating , Fasting , Female , Humans , Immunoenzyme Techniques , Liver Function Tests , Male , Middle Aged , RadioimmunoassayABSTRACT
Treatment of pregnant rats with ursodeoxycholic acid or chenodeoxycholic acid at 3 dose levels resulted in no dismorphogenic effects although embryotoxicity and fatty infiltration in maternal liver were more frequent after CDCA. Light microscopic examination showed no evidence of derangement in fetal liver. Electron microscopic study, carried out in maternal liver, showed that changes were present only in dams treated with the highest doses of both bile acids.
Subject(s)
Chenodeoxycholic Acid/toxicity , Deoxycholic Acid/analogs & derivatives , Embryo, Mammalian/drug effects , Pregnancy, Animal/drug effects , Ursodeoxycholic Acid/toxicity , Animals , Female , Fetal Death/chemically induced , Liver/pathology , Male , Pregnancy , RatsSubject(s)
Bridged Bicyclo Compounds/therapeutic use , Bridged-Ring Compounds/therapeutic use , Colonic Diseases, Functional/drug therapy , Cyclohexanecarboxylic Acids , Endoscopy , Parasympatholytics/therapeutic use , Adult , Aged , Colonic Diseases, Functional/diagnosis , Endoscopy/adverse effects , Female , Humans , Male , Middle Aged , Nausea/drug therapy , Vomiting/drug therapySubject(s)
Bile Acids and Salts/blood , Liver Diseases/diagnosis , Adolescent , Adult , Aged , Chronic Disease , Clinical Enzyme Tests , Female , Hepatitis/blood , Hepatitis/diagnosis , Humans , Liver Cirrhosis/blood , Liver Cirrhosis/diagnosis , Liver Diseases/blood , Liver Function Tests , Male , Middle AgedSubject(s)
Bile Acids and Salts/blood , Liver Diseases/diagnosis , Adolescent , Adult , Aged , Chronic Disease , Female , Humans , Liver Diseases/blood , Liver Function Tests , Male , Middle AgedSubject(s)
Ascites/therapy , Dialysis/methods , Liver Cirrhosis/therapy , Adolescent , Adult , Aged , Chronic Disease , Female , Humans , Liver Cirrhosis/complications , Male , Middle AgedABSTRACT
A functional study was made of 40 patients with bioptically diagnosed CPH. Fractional BSF clearance was the most frequently altered test and its correlation with the anatomical damage was significant. In particular, the fractional uptake clearance (K1) gave a pointer to both the presence of liver damage and its type. Elimination clearance (K2) may also be useful, especially in the differentiation of histological pictures on the borderline between CAH and CPH. In the evaluation of CPH, therefore, BSF clearance is of marked assistance both in rounding out the histological diagnosis, and in cutting down the need for control biopsies.
