ABSTRACT
AD is the highly severe part of the dementia spectrum and impairs cognitive abilities of individuals, bringing economic, societal and psychological burdens beyond the diseased. A promising approach in AD research is the analysis of structural and functional brain connectomes, i.e., sNETs and fNETs, respectively. We propose to use tensor representation (B-tensor) of uni-modal and multi-modal brain connectomes to define a low-dimensional space via tensor factorization. We show on a cohort of 47 subjects, spanning the spectrum of dementia, that diagnosis with an accuracy of 77% to 100% is achievable in a 5D connectome space using different structural and functional connectome constructions in a uni-modal and multi-modal fashion. We further show that multi-modal tensor factorization improves the results suggesting complementary information in structure and function. A neurological assessment of the connectivity patterns identified largely agrees with prior knowledge, yet also suggests new associations that may play a role in the disease progress.
Subject(s)
Alzheimer Disease , Connectome , Alzheimer Disease/diagnostic imaging , Brain/diagnostic imaging , Humans , Magnetic Resonance ImagingABSTRACT
In the absence of surgery on the urinary tract, the emission of red urine after anesthesia should be considered as a diagnostic emergency because it can be a sign of hematuria, hemoglobinuria, blood transfusion reaction, significant myoglobinuria, or porphyria.This case describes the management of a 12-year-old boy who presented red urine at the day care unit after strabismus surgery.
Subject(s)
Ambulatory Surgical Procedures/adverse effects , Day Care, Medical , Myoglobinuria/diagnosis , Rhabdomyolysis/diagnosis , Strabismus/surgery , Child , Day Care, Medical/trends , Humans , Male , Myoglobinuria/etiology , Myoglobinuria/therapy , Postoperative Complications/diagnosis , Postoperative Complications/etiology , Postoperative Complications/therapy , Rhabdomyolysis/therapy , Strabismus/diagnosisABSTRACT
Most of the errors encountered during drug applications of anaesthesia may arise from the selection of the wrong syringe and ampule, confusion of epidural and intravenous line, or incorrect dose administration. In this case report, accidental application of reversal drugs via epidural catheter to a patient who was operated on for ureterovesical stenosis is presented. We aimed to indicate the drug errors in anaesthesia practices and discuss measures to be taken to prevent it.
