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Vet Rec ; 161(8): 265-8, 2007 Aug 25.
Article in English | MEDLINE | ID: mdl-17720963

ABSTRACT

Doses of 12.5 mg voriconazole/kg bodyweight administered every 12 hours by crop gavage to six falcons for 14 days provided peak plasma concentrations of more than 1 microg/ml, but the trough concentrations were lower and sometimes undetectable. Administering the same doses incorporated into meat that was fed to one falcon for seven days and to three falcons for up to 91 days provided similar plasma concentrations.


Subject(s)
Antifungal Agents/blood , Aspergillosis/veterinary , Bird Diseases/drug therapy , Falconiformes/blood , Pyrimidines/blood , Triazoles/blood , Animals , Antifungal Agents/administration & dosage , Antifungal Agents/pharmacokinetics , Aspergillosis/drug therapy , Biological Availability , Dose-Response Relationship, Drug , Female , Male , Pyrimidines/administration & dosage , Pyrimidines/pharmacokinetics , Treatment Outcome , Triazoles/administration & dosage , Triazoles/pharmacokinetics , Voriconazole
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