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1.
Bone tumours induced in rats with radioactive cerium.
Delbrück, H G; Allouche, M; Jasmin, C; Morin, M; Deml, F; Anghileri, L; Masse, R; Lafuma, J.
Br J Cancer ; 41(5): 809-15, 1980 May.
Article in English | MEDLINE | ID: mdl-6932906

ABSTRACT

A technique is described for the induction of metastasizing bone tumours in rats by local inoculation of 144cerium. Bone sarcomas develop in 90% of the animals and 74% of these had lung metastases. The tumours can be easily cultured and maintained by serial transplantations. Preliminary data of clinical, histological and kinetic characteristics of these bone tumours are given.


Subject(s)
Bone Neoplasms/etiology , Cerium Radioisotopes , Hemangiosarcoma/etiology , Neoplasms, Radiation-Induced/etiology , Osteosarcoma/etiology , Animals , Bone Neoplasms/pathology , Cell Count , Cells, Cultured , Disease Models, Animal , Hemangiosarcoma/pathology , Lung Neoplasms/secondary , Male , Neoplasms, Radiation-Induced/pathology , Osteosarcoma/pathology , Rats , Sarcoma, Experimental/etiology , Sarcoma, Experimental/pathology
2.
[Stimulation of DNA synthesis in intact rat livers using serum beta globulins]. / Stimulace syntézy DNA v intaktních játrech krys sérovými beta-globuliny.
Kanta, J; Bartos, F; Simek, J; Deml, F.
Sb Ved Pr Lek Fak Karlovy Univerzity Hradci Kralove Suppl ; 21(2): 159-76, 1978.
Article in Czech | MEDLINE | ID: mdl-82274

Subject(s)
Beta-Globulins/pharmacology , DNA/biosynthesis , Liver/metabolism , Animals , Cattle , Hepatectomy , Humans , Liver Regeneration/drug effects , Rats
3.
[Quantitative evaluation of protein-binding interactions]. / Ke kvantitativnímu hodnocení proteinových vazebnostních interakcí
Deml, F; Kvetina, J; Láznícek, M.
Cesk Farm ; 24(9): 386-9, 1975 Nov.
Article in Czech | MEDLINE | ID: mdl-1218405

Subject(s)
Protein Binding , Biopharmaceutics , Humans , Sulfameter/metabolism
4.
[Changes in the synthesis of desoxyribonucleic acid and in the ultrastructure of the liver after administration of endotoxin in rats with partial hepatectomy (author's transl)]. / Veränderungen der Synthese der Desoxyribonukleinsüre und der Ultrastruktur der Leber nach Applikation von Endotoxin an Ratten mit partieller Hepatektomie.
Simek, J; Tichý, J; Melka, J; Vosyková, A; Vejbora, O; Deml, F.
Acta Hepatogastroenterol (Stuttg) ; 20(4): 307-14, 1973.
Article in German | MEDLINE | ID: mdl-4760415

Subject(s)
DNA/biosynthesis , Endotoxins/pharmacology , Hepatectomy , Liver/metabolism , Acid Phosphatase/metabolism , Alkaline Phosphatase/metabolism , Animals , Endoplasmic Reticulum/drug effects , Female , Liver/cytology , Liver/enzymology , Liver Regeneration/drug effects , Mitochondria, Liver/drug effects , Rats
5.
Deoxyribonucleic acid synthesis in rat liver and kidney after the injection of Cohn fraction 3 of human serum.
Kanta, J; Simek, J; Bartos, F; Deml, F.
Exp Pathol (Jena) ; 8(4): 287-93, 1973.
Article in English | MEDLINE | ID: mdl-4130142

Subject(s)
Beta-Globulins/pharmacology , DNA/biosynthesis , Kidney/metabolism , Liver/metabolism , Animals , Carbon Radioisotopes , Cell Count , DNA Replication , Hepatectomy , Humans , Kidney/cytology , Kidney/physiology , Lipid Metabolism , Liver/cytology , Liver/physiology , Liver Regeneration , Mitosis , Nephrectomy , Orotic Acid/metabolism , Rats , Regeneration , Serum Albumin, Bovine/pharmacology , Thymidine/metabolism
6.
The effect of starvation on changes in lipid content and DNA synthesis in the liver of rats after partial hepatectomy.
Simek, J; Husáková, A; Deml, F.
Physiol Bohemoslov ; 19(1): 101-6, 1970.
Article in English | MEDLINE | ID: mdl-4248987

Subject(s)
DNA/biosynthesis , Hepatectomy , Lipid Metabolism , Liver/metabolism , Starvation , Animals , Carbon Isotopes , Female , Lipids/analysis , Phospholipids/analysis , Rats , Thymine/metabolism , Time Factors , Triglycerides/analysis
7.
Hepatic DNA synthesis after partial hepatectomy in rats treated with protamin-Zn-insulin under different nutritional conditions.
Simek, J; Husáková, A; Deml, F; Dvorácková, I.
Experientia ; 25(8): 791-2, 1969 Aug 15.
Article in English | MEDLINE | ID: mdl-5348528

Subject(s)
DNA/biosynthesis , Insulin, Long-Acting/pharmacology , Liver Regeneration/drug effects , Liver/metabolism , Animal Nutritional Physiological Phenomena , Animals , Carbon Isotopes , Depression, Chemical , Dietary Carbohydrates , Dietary Fats , Dietary Proteins , Hepatectomy , Male , Rats , Thymidine/metabolism
8.
Gastric retention and its changes in mice and rats during the first six days following x-irradiation.
Chmelar, V; Grossmann, V; Hais, I M; Deml, F.
Radiat Res ; 37(3): 627-35, 1969 Mar.
Article in English | MEDLINE | ID: mdl-5775546

Subject(s)
Gastrointestinal Motility/radiation effects , Intestinal Absorption/radiation effects , Radiation Effects , Stomach/radiation effects , Animals , Autoradiography , Calcium Chloride/blood , Calcium Chloride/metabolism , Carbon Isotopes , Glycine/blood , Glycine/metabolism , Mice , Rats , Sodium/blood , Sodium Isotopes , Sulfates/blood , Sulfates/metabolism
9.
Liver regeneration after partial hepatectomy in rats exposed before the operation to the stress stimulus.
Simek, J; Erbenová, Z; Deml, F; Dvorácková, I.
Experientia ; 24(11): 1166-7, 1968 Nov 15.
Article in English | MEDLINE | ID: mdl-4305510

Subject(s)
Liver Regeneration , Stress, Physiological , Adrenocorticotropic Hormone/pharmacology , Animals , DNA/biosynthesis , Hepatectomy , Rats
10.
Distribution of PABA and 14C-labelled PABA in rat organism and its changes during post-irradiation disease.
Fendrich, Z; Kvetina, J; Deml, F; Grossmann, V.
Sb Ved Pr Lek Fak Karlovy Univerzity Hradci Kralove ; 11(5): 759-63, 1968.
Article in English | MEDLINE | ID: mdl-5257746

Subject(s)
Aminobenzoates/analysis , Radiation Injuries, Experimental/metabolism , Animals , Autoradiography , Carbon Isotopes , Female , Injections, Intravenous , Rats
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