1.
Clin Chem
; 24(10): 1674-9, 1978 Oct.
Article
in English
| MEDLINE
| ID: mdl-699272
ABSTRACT
We describe a complete procedure for separation and mechanized analysis of organic acids in human urine. The acid fraction of urine is separated by anion-exchange chromatography on diethylaminoethyl-Sephadex. Individual acids are identified and measured by use of a gas-chromatography/mass spectrometer/computer system that can clearly distinguish contributions from at least 150 substances in a single sample. We discuss analytical recoveries, contributions from the sample separation process, stability of stored samples before and after processing, and reproducibility of the extraction procedure.
Subject(s)
Carboxylic Acids/urine , Autoanalysis/methods , Carboxylic Acids/isolation & purification , Chromatography, Gas , Chromatography, Ion Exchange/methods , Drug Stability , Humans , Mass Spectrometry , Specimen Handling
2.
Biochem Med
; 18(1): 87-95, 1977 Aug.
Article
in English
| MEDLINE
| ID: mdl-901435