ABSTRACT
OBJECTIVE: To explore the current condition of psychological problems of patients in cardiology clinic. METHODS: A total of 347 patients in the cardiology clinic of Prof. HU Da-yi were screened by self-rating depression scale (SDS), Self-rating anxiety scale (SAS), Hamilton rating scale for depression (HRSD) and Hamilton anxiety scale (HAMA). RESULTS: The rates of patients with somatic disease only or with psychological disorder only were 52.4% and 12.7%, the rate of somatic disease accompanied with psychological disorder was 27.7%. For the patients with psychological problems, there were 31 cases with depression (8.9%), 62 cases with anxiety (17.9%), and 28 cases (8.1%) suffering from mixed depression and anxiety the diagnosis of cardiovascular disease, functional disease or digestive disease was always used by doctors for the patients with psychological problems only, as they always did not accept the diagnosis of psychological disorder. CONCLUSIONS: It is very common that patients in cardiology clinic department suffered from psychological problems. The patients with psychological disorder only were easily misdiagnosed as somatic disease especially cardiovascular disease.
Subject(s)
Coronary Artery Disease/psychology , Outpatients/psychology , Adult , Anxiety/etiology , Anxiety/psychology , Coronary Artery Disease/complications , Depression/etiology , Depression/psychology , Female , Humans , Male , Middle Aged , Outpatients/statistics & numerical data , Psychiatric Status Rating ScalesABSTRACT
Objective To investigate the effect of low frequency electric deep brain stimulation on amygdale kindling in rats.Methods The amygdale kinkling model of rats was established by operation on the brain.The effects of low frequency deep brain electric stimulation used alone or in combination with anti-epilepsy drugs were ob- served in terms of severity of seizure attack reflected by Racine's scale and afterdischarge duration recorded in electro- encephalogram.Results Fifteen minutes of low frequency electric stimulation at 1 Hz and 100 to 350?A effective- ly inhibited amygdale kindling as demonstrated by a significant decrease of afterdischarge duration,and decreased the severity of seizure attack (P
ABSTRACT
Objective To invesgate the effect of P-glycoprotein(PGP)inhibitor,verapamil,on electrobiological activity and seizure behavior in phenytoin-carbamazepine(PHT-CBZ)resistant rats.Methods The model of medically intractable epilepsy was established by kindling of amygdale. Verapamil was applied to PHT-CBZ resistant rats,followed by the observation on after discharge threshold (ADT),after discharge duration(ADD)and seizure activity.Results Compared with the control group, the ADT was higher in PHT-CBZ resistant rats peritoneally injected with verapamil((238.0?32.2)?A vs (177.0?23.3)?A,P
