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1.
Urolithiasis ; 51(1): 53, 2023 Mar 17.
Article in English | MEDLINE | ID: mdl-36930293

ABSTRACT

This study was aimed at investigating the impact of varying concentrations of strontium (Sr) on calcium (Ca) excretion via the urine and determine its impact on kidney stone formation. Twenty adult male Sprague Dawley rats weighing between 200 and 300 g were selected. The rats were randomly divided into four groups of five. One group was used as a control group while the other three groups were experimental. The diet of the rats was modulated over a 12 week period to investigate the impact of Sr on the urinary excretion of Ca. Urinary samples were collected every 2 weeks from the rats. The rats were fed water ad libitum. After the study the rats were euthanised and their kidneys harvested. Urine and kidney samples from the rats were analysed using Total Reflection X-Ray Fluorescence (TXRF). In the urine excretion of Ca increased with increased intake of Sr in the diet. Sr excretion via the urine also increased with increased dietary intake. There was a correlation of 0.835 at the significance level of 0.01 between Ca and Sr in the urine. However, for the kidneys, the varying concentration of Sr did not impact the retention of Ca in the kidneys. There was increased retention of Sr in the kidneys with increased dietary intake. In this study an increase of Sr in the diet resulted in an increase in urinary excretion of Ca.


Subject(s)
Calcium , Strontium , Rats , Male , Animals , Calcium/urine , Rats, Sprague-Dawley , Strontium/urine , Calcium, Dietary , Kidney
2.
Radiat Environ Biophys ; 61(2): 325-334, 2022 05.
Article in English | MEDLINE | ID: mdl-35411404

ABSTRACT

Atmospheric dispersion modeling was performed for a postulated design basis accident at a SLOWPOKE research reactor. The MCNP-5 computer code was used to estimate the neutron flux spectrum which was then used in the ORIGEN-S code to perform core depletion calculations and determine the radiological source term. The HotSpot health physics code was then used to model the atmospheric transport of the radioactive material released to estimate the resulting doses to the population downwind of the reactor. The highest total effective dose (TED) for a release from the reactor's exhaust stack in predominant meteorological conditions, stability class C, was 0.37 mSv, while a maximum TED of 4.29 mSv was estimated for a release at ground level. Ground deposition was estimated to be 3900 kBq/m2. It was shown that any hypothetical release of radioactive material resulting from such an accident would have no significant adverse effect on the municipal water reservoir close to the reactor.


Subject(s)
Air Pollutants, Radioactive , Radiation Monitoring , Radioactive Hazard Release , Air Pollutants, Radioactive/analysis , Neutrons
3.
Appl Radiat Isot ; 129: 152-155, 2017 Nov.
Article in English | MEDLINE | ID: mdl-28863288

ABSTRACT

Analysis was performed to estimate radiation levels during removal and packaging of the highly-enriched uranium core of the JM-1 SLOWPOKE-2 research reactor. Due to severe limitations of space in and around the reactor pool, the core could not be removed in the conventional manner as was done for previous SLOWPOKE defuelling operations. A transfer shield, with a balance between shielding efficacy, volume and weight was designed. Fuel depletion, Monte Carlo shielding and criticality calculations were performed. Comparisons of measured and calculated dose rates as well as results of the criticality safety assessment are presented. The designed transfer shield reduced the calculated unshielded dose rate from 29Sv/h to 8mSv/h. The maximum calculated effective neutron multiplication factor of approximately 0.89 was below the 0.91 upper subricital limit.

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