ABSTRACT
While guidance on how to design rigorous evaluation studies abounds, prescriptive guidance on how to include critical process and context measures through the construction of exposure variables is lacking. Capturing nuanced intervention dosage information within a large-scale evaluation is particularly complex. The Building Infrastructure Leading to Diversity (BUILD) initiative is part of the Diversity Program Consortium, which is funded by the National Institutes of Health. It is designed to increase participation in biomedical research careers among individuals from underrepresented groups. This chapter articulates methods employed in defining BUILD student and faculty interventions, tracking nuanced participation in multiple programs and activities, and computing the intensity of exposure. Defining standardized exposure variables (beyond simple treatment group membership) is crucial for equity-focused impact evaluation. Both the process and resulting nuanced dosage variables can inform the design and implementation of large-scale, diversity training program, outcome-focused, evaluation studies.
ABSTRACT
The open source software tools developed at UCLA are the informatics infrastructure supporting translational research efforts of the 11 National Cancer Institutes Prostate SPORE sites. The Codebook is a caBIG compliant application that manages PHI (e.g. names, medical record numbers, etc.) separately from research data. Research data are collected using a flexible clinical trials management suite called pTracker. Our poster will present how these two applications are implemented and function in this prospective multi-center study.
Subject(s)
Biological Specimen Banks/organization & administration , Biomarkers , Database Management Systems , Prostatic Neoplasms/diagnosis , Computational Biology , Computer Communication Networks , Humans , Intellectual Property , Male , Medical Records Systems, Computerized , Prospective Studies , Systems IntegrationABSTRACT
Separating personal health information (PHI) from research data is a critical issue. In our work the Central CodeBook (CCB) functions as an 'honest broker' by mapping between internally meaningful, subject codes (IDs) and sensitive external identifiers like medical record numbers. The CCB is a web service enabled database-backed web application that brokers communications with our evolving EMR via the Clinical Information Network Exchange (CNEX).
