ABSTRACT
Results of the experiments carried out show that the use of the activated carbon fibrous material "Dnipro" for medical purposes (ABBM "Dnipro" MP) and the suspension of high-dispersity iron combined in treatment of infected and suppurating wounds is associated with a more pronounced therapeutical effect than application to the wound surfaces of the standard ABBM "Dnipro" MP. The compositional method using ABBM "Dnipro" MP and high-dispersity iron obtainable by thermochemical techniques has a marked antimicrobial action and stimulates the course of the wound process.
Subject(s)
Anti-Infective Agents/administration & dosage , Charcoal/administration & dosage , Iron/administration & dosage , Wound Healing/drug effects , Absorption , Animals , Drug Combinations , Drug Evaluation, Preclinical , Pseudomonas Infections/drug therapy , Pseudomonas Infections/microbiology , Pseudomonas Infections/pathology , Rats , Staphylococcal Infections/drug therapy , Staphylococcal Infections/microbiology , Staphylococcal Infections/pathology , Suspensions , Time Factors , Wound Infection/drug therapy , Wound Infection/microbiology , Wound Infection/pathologyABSTRACT
High-dispersed magnetized iron preparations of various coercive force and its preparations with Ag, Au, Pt obtained by thermochemical method have been studied for their effect on plants and bacteria pathogenic for animals. It is established that magnetized iron intensifies antibacterial effect of certain metals. Of the studied preparations only high-dispersed Fe-Ag had distinctly expressed bactericidal effect. Other preparations had weak antibacterial effect or had not it at all. All the preparations have strong adsorption capacity.