1.
Org Lett
; 3(2): 201-3, 2001 Jan 25.
Article
in English
| MEDLINE
| ID: mdl-11430034
ABSTRACT
[figure: see text] An efficient, high-yielding strategy has been developed for the asymmetric synthesis of 1-N-iminosugars (1-azasugars), a new class of glycosidase inhibitors with promising biomedical applications. A highly regioselective procedure for the 1,2-reduction of substituted pyridines was employed to transform methyl nicotinate into several representative 1-azasugars.