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1.
Pediatrie ; 38(8): 523-31, 1983 Dec.
Article in French | MEDLINE | ID: mdl-6674921

ABSTRACT

The authors have studied platelet aggregability in the presence of ADP and collagen in a population of 40 migrainous children between migraine attacks. They completed their investigations by a qualitative dosage in platelets and in plasma of fatty acids, precursors of prostaglandins, which are well known for their importance in platelet aggregation and vasculomotor reactions. This study was made in comparison with an equal number of controls chosen from the same age-groups. The authors didn't find the hyperaggregability observed by other authors in grown-up populations. They noticed a light-but statistically significant-diminution of linoleic acid in the platelets and in the plasma. A study based on observations does not entirely confirm for certain an alimentary origin.


Subject(s)
Fatty Acids/blood , Migraine Disorders/blood , Platelet Aggregation , Adolescent , Blood Platelets/analysis , Child , Female , Humans , Linoleic Acid , Linoleic Acids/blood , Male , Prostaglandins/blood
5.
Arch Neurol ; 33(10): 724-5, 1976 Oct.
Article in English | MEDLINE | ID: mdl-184767

ABSTRACT

Muscle biopsy specimens from two half brothers with a congenital benign muscle disorder and from their mother, clinically unaffected, were studied by histochemistry and electron microscopy. In the children's biopsy specimens, the ultrastructural examination showed numerous fingerprint bodies located at the periphery of the muscle fibers. The histochemical pattern was different in these two specimens. In the mother's biopsy specimen, while fingerprint bodies were not found, the muscle fibers showed slight but definite changes. Even if the fingerprint bodies by themselves are not specific for a particular muscle disease, their occurrence in two half brothers is a valid argument in favor of the individalization of the fingerprint body myopathy, which has been previously described.


Subject(s)
Muscles/ultrastructure , Muscular Diseases/pathology , Adult , Child , Female , Humans , Inclusion Bodies/ultrastructure , Infant , Male , Muscular Diseases/genetics
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