ABSTRACT
Objective To explore the clinical value of N-terminal pro-brain natriuretic peptide (NT-proBNP) in elderly patients with acute dyspnea .Methods Retrospective analysis of 146 cases of patients with emergency admissions of patients(age ≥60 years)with dyspnea from January 2012 ~December 2013,patients in 2012 with conventional treatment group; patients in 2013 were under the guidance of NT-proBNP treatment group; properties according to the test results of the NT-proBNP clinical reference standard and NT-proBNP to the evaluation of dyspnea and guide rescue,rescue success rate of patients in 2 groups were analyzed and compared .Results 67 cases (15 ca-ses were markedly effective ,37 cases were effective ,11 cases were invalid ,4 cases of death ) were rescued in 2012, 79 cases (27 cases were markedly effective ,44 cases were effective,6 cases were invalid,2 cases of death) were res-cued in 2013.Elderly patients with Dyspnea under the guidance of emergency NT-proBNP levels in 2013(89.87%), the rescue success rate was higher than that in the 2012 traditional treatment group (77.61%) (χ2 =4.11,P <0.05).Conclusion Rapid determination of NT-proBNP level of elderly patients with dyspnea has high clinical value in emergency rescue .
ABSTRACT
Objective To explore the clinical prognostic value of rapid detection for plasma NT-proBNP levels on admission in patients with acute myocardial infarction.Methods 56 patients with AMI were measured plasma NT-proBNP imediately in hospital,and then they were divided into A,B and C group according to NT-proBNP levels (A group:＜ 500ng/L,B group:500-2 000ng/L,C group:＞ 2 000ng/L).The incidence of major adverse cardiac events (MACE including congestive heart failure,malignant arrhythmia,cardiogenic shock and sudden cardiac death) in subjects were observed respectively during hospitalisation and 30 days.Results The three group subjects with different NT-proBNP levels presented different incidence of MACE(A group:1,0;B group:3,1;C group:8,6) at duration of hospital stay,30days (x2 =6.705,P =0.035 ; x2 =7.957,P =0.008).With the NT-proBNP levels rising in AMI paitents,the inciedence of MACE increased.The incidence of MACE in A,B and C group were 6.6％,18.18％ and 73.69％ respectively.Conclusion In AMI patients,plasma NT-proBNP levels could predict early MACE incidence,which has an important value to evaluate the early clinical prognosis.
