Breast Masses Detection and Segmentation in Full-Field Digital Mammograms using Unified Convolution Neural Network.

Breast Cancer has been the primary reason for mortality in women of age between twenties and sixties worldwide; moreover early detection and treatment provides patients to get absolute treatment and decrease the mortality rate. Furthermore, recent research indicates that most experienced physicians have plenty of limitations, hence the plethora of work has been carried out to develop an automated mechanism of segmentation and classification of affected area and type of cancer; however, it is still considered to be highly challenging due to the variability of tumor in shape, low signal to noise ratio, shape, size and location of tumor. Furthermore, mammographic mass segmentation and detection are performed as a separate task and a convolution neural network is a highly adopted architecture for the same. In this research, we have designed and developed unified CNN architecture to perform the segmentation and detection of a breast mass. The unified-CNN architecture comprises a novel module for convolution which is combined through additional offset. Further RRS aka Random Region Selection mechanism is applied for data augmentation approach and high-level feature map is implied to achieve the high prediction. Furthermore, unified-CNN is evaluated using the metrics like true positive Rate at FPI (False Positive per Image) and Dice Index on INBreast dataset, also comparative analysis is out carried with various existing methodology. Unified-CNN is developed through improvising CNN. It introduces a novel module at the convolution layer to aim for a high-level feature map in order to get a high prediction. RRS (Random Region Selection) algorithm is used as the data augmentation approach to select the boundary region of the affected area; further robust model training is designed and optimized for process to make optimal. Unified-CNN introduces novel module at the convolution layer to aim for high level feature map in order to get high prediction; further ROI pooling is utilized for boundary detection in images.

Automated diagnosis of Coronary Artery Disease using pattern recognition approach.

Coronary Artery Disease (CAD) is the most leading Cardiovascular Disease (CVD), which results due to buildup of plaque inside the coronary arteries. The CAD and Normal Sinus Rhythm (NSR) heartbeats can be discriminated and diagnosed noninvasively using the standard tool Electrocardiogram (ECG). However, manual diagnosis of ECG is tiresome and time consuming task, due to complex nature and unseen nonlinearities of ECG. Hence an automated system plays a substantial role. In this study, CAD and NSR heartbeats are discriminated and diagnosed using Higher-Order Statistics (HOS) cumulants features. Further, the cumulants coefficients dimensionality reduced using Principal Components Analysis (PCA) and the medically significant features (p-value<;0.05) Principal Components (PCs) are subjected for classification using Random Forest (RAF) and Rotation Forest (ROF) ensemble classifiers. Proposed system is robust which helps in screening CAD risk factors and telemonitoring applications.

Using technology and collaborative working for a positive patient experience and to improve safety.

Clinicians who treat patients with wounds need access to the resources that will enable them to deliver the best and most appropriate treatments. A partnership working initiative between Greenwich CCG Medicines management (commissioner), Oxleas NHS Foundation Trust (provider) and ConvaTec (commercial partner) was set up to provide wound-care dressings and products to patients via the community services. It lead to improved access, greater patient benefits, a reduction in dressings waste, and an increase in clinical confidence to make cost-effective, evidence-based prescribing decisions. This inspired the commissioners to collaborate with BlueBay (technology partner) to 'trailblaze' the development and introduction of an electronic wound care template for practice nurses and doctors in primary care to use in conjunction with VISION and EMIS, clinical software systems used in GP practices. This interoperability of clinical systems to improve wound care is, to date, the only one of its kind in the UK.