ABSTRACT
A 69-year-old woman with an enlarging ascending aortic aneurysm is presented. At operation, the patient was noted to have extensive peri-aneurysmal fibrosis and inflammation with a 1 cm thick aneurysm wall. Pathologic examination was consistent with inflammatory aneurysm. Inflammatory aneurysms of the thoracic aorta are uncommon and this may be the first patient with this process involving the ascending aorta with both operative and pathologic findings.
Subject(s)
Aortic Aneurysm , Aortitis , Aged , Aorta/pathology , Aortic Aneurysm/diagnostic imaging , Aortic Aneurysm/pathology , Aortitis/diagnostic imaging , Aortitis/pathology , Female , Humans , Tomography, X-Ray ComputedABSTRACT
The homologous nature and morphological similarities between cutaneous and salivary gland tumors have been well documented. This is especially true of the monomorphic adenoma, eccrine spiradenoma and cylindroma. Prior to the first full clinical and pathological description, about twenty-five years ago, the lesion of eccrine spiradenoma had been given multiple synonyms. This report is of a patient with an eccrine spiradenoma in the buttock and dermaltype cylindroma of the parotid gland. This may represent the transformation of pleuripotential basal cells originating in the parotid and eccrine sweat gland.
Subject(s)
Adenoma, Sweat Gland/pathology , Carcinoma, Adenoid Cystic/pathology , Neoplasms, Multiple Primary/pathology , Parotid Neoplasms/pathology , Sweat Gland Neoplasms/pathology , Adult , Buttocks , Humans , MaleABSTRACT
A women with non-Hodgkin's lymphoma developed numerous sebaceous adenomas over the face, neck, and trunk. The association of multiple sebaceous adenomas with underlying visceral malignancy was first described by Torre in 1968 and is known now as Torre's syndrome. The present case, to the best of our knowledge, is the first report of hematologic malignancy associated with Torre's syndrome.
Subject(s)
Adenoma/etiology , Head and Neck Neoplasms/etiology , Keratoacanthoma/etiology , Lymphoma/complications , Sebaceous Gland Neoplasms/etiology , Adenoma/pathology , Female , Humans , Keratoacanthoma/pathology , Middle Aged , Paraneoplastic Syndromes/etiology , SyndromeABSTRACT
A case of fulminant hepatic failure leading to death in a patient receiving DTIC for metastatic melanoma is presented. Autopsy revealed widespread centrilobular necrosis secondary to a veno-occlusive process. There was no evidence of a similar process in other organs, and common causes of similar pathology were ruled out. It is likely that in this patient the hepatic failure was due to DTIC alone. Similar cases have been reported in patients receiving other chemotherapeutic agents. Physicians using these drugs should be aware of this side-effect of therapy, since it is often fatal.
