ABSTRACT
BACKGROUND: Acute stroke (AS) rates in patients over 90 years of age (very elderly) with atrial fibrillation (AF) in the United States (US) are not known. We assessed trends in hospitalizations for AS among very elderly with AF in the US from 2005 to 2014. METHODS: We used the nationwide inpatient sample (NIS) from the USA; 2005-2014. AF and AS diagnoses were abstracted using international classification of diseases, 9th Revision, clinical modification (ICD-9-CM) codes. RESULTS: From 2005 to 2014, 3,606,073 hospitalizations of very elderly with AF were reported. Of these, 188,948 hospitalizations (141,822 hospitalizations in women and 47,126 hospitalizations in men) had AS as the primary diagnosis. Age adjusted AS hospitalizations increased in the total cohort (3217/million in 2005 to 3871/million in 2014), in women (3540/million in 2005 to 4487/million in 2014) and in men (2490/million in 2005 to 3173/million in 2014) (P < 0.001). Anticoagulation rates increased in women (8% in 2005 to 19.9% in 2014) and in men (8.9% in 2005 to 21.6% in 2014). AS rates, though numerically lower than the total cohort, showed an increasing trend in anticoagulated patients as well (all anticoagulated patients: 212/million in 2005 to 513/million in 2014; anticoagulated women: 224/million in 2005 to 529/million in 2014, anticoagulated men: 184/million in 2005 to 518/million in 2014). CONCLUSIONS: There is an increasing trend in AS hospitalizations among nonagenarians with AF in the US despite improving utilization of anticoagulants in this patient population. The etiologies driving this alarming trend are unclear and require further study.
ABSTRACT
UNLABELLED: As the number of patients undergoing catheter ablation for atrial fibrillation (AF) increases, there is a growing focus on optimizing the quality and efficiency of. Readmission is often considered an indicator of both quality and efficiency of care delivery. We sought to estimate rates and identify predictors of readmission after catheter ablation. METHODS AND RESULTS: Using a large, national administrative claims database, we identified all AF patients who underwent catheter ablation between January 2009 and December 2013 (10,705 ablation cases). We examined incident readmission and the primary diagnosis during the readmission episode of care. We used Cox proportional hazard models to identify associations between readmission and patient and institutional characteristics. A total of 1,433 (13.4%) ablation patients were readmitted within 90 days of ablation for any cause, and 573 (5.4%) were admitted with AF as the primary diagnosis. There was a decline in all-cause (from 15.6% to 12.8%; P = .04) and AF-related (6.4%-5.0 %; P = .03) 90-day readmission over the study period. In a multivariate model, earlier year of ablation and each of 9 chronic conditions (alone or in combination) were independently associated with risk of readmission. CONCLUSIONS: Between 2009 and 2013, there was a reduction in 90-day readmission rates after AF ablation, suggesting improved periprocedural care of these patients. Identifying patients at high risk for readmission after catheter ablation for AF may offer an opportunity for early intervention and, ultimately, reduction in procedural morbidity and medical costs.
