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Vopr Med Khim ; 33(1): 79-84, 1987.
Article in Russian | MEDLINE | ID: mdl-3577064

ABSTRACT

High molecular fraction of HCl-extract from mature homologous bone was parenterally administered, during the predistraction period, into 16 rabbits, crus of which was elongated by Ilizarov procedure. The treatment affected positively the adaptation process, hemopoiesis and the ossification of distraction regenerate. Administration of the high molecular protein fraction into mice with depressed hemopoiesis demonstrated that physiological effect of the fraction consisted in stimulating effect on proliferation of both bone tissue and red blood cells.


Subject(s)
Bone Lengthening/methods , Bone Matrix/physiology , Hematopoiesis , Osteogenesis , Proteins/physiology , Animals , Blood Cell Count , Bone Matrix/analysis , Mice , Molecular Weight , Proteins/analysis , Rabbits , Tissue Extracts/pharmacology
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