ABSTRACT
The authors report a case of a patient arrived at their observation in cardiogenic shock. The ECG showed extreme bradycardia refractory to resuscitation manoeuvres. The autopsy showed a lipomatous hamartoma in the interatrial septum. The lipomatous hamartoma is a primitive cardiac tumor, very rare, with an usually asymptomatic course but with severe prognosis. The authors emphasize that clinical presentation can be aspecific and resembling several other diseases, and early identification can be achieved only by 2D echo-cardiography or nuclear magnetic resonance imaging.
Subject(s)
Death, Sudden, Cardiac/etiology , Hamartoma/diagnosis , Heart Neoplasms/diagnosis , Lipoma/diagnosis , Autopsy , Diagnosis, Differential , Fatal Outcome , Female , Hamartoma/complications , Heart Neoplasms/complications , Heart Septum , Humans , Lipoma/complications , Middle AgedSubject(s)
Alcoholism/complications , Cardiomyopathies/etiology , Adult , Cardiomyopathies/diagnosis , Echocardiography , Hemodynamics , Humans , Male , Middle Aged , Myocardial Contraction , Risk , SystoleSubject(s)
Myocardial Infarction/etiology , Adult , Age Factors , Diabetes Complications , Follow-Up Studies , Humans , Hyperlipidemias/complications , Male , Obesity/complications , Risk , SmokingABSTRACT
The clinical usefullness of the CPK MB test (spectophotometric method) was evaluated on 139 patients admitted to a Cardiovascular Diseases Department with a diagnosis of suspected myocardial infarction. Serial determinations of serum MB isoenzyme creatine kinase, total creatine kinase, lacate dehydrogenase and hydrossibutirrate dehydrogenase were made at 1st, 2th, 3th, 4th, 5th, 6th, 7th day. Incidence of CPK MB false positive and false negative data were also determined and correlated with the electrocardiogram pattern and serum levels of other standard enzymes. Results indicate that the CPK MB kinetic test is highly specific (94%) and promptly available in the early diagnosis of acute myocardial infarction.
