1.
Biochim Biophys Acta
; 386(2): 538-41, 1975 Apr 29.
Article
in English
| MEDLINE
| ID: mdl-1138885
ABSTRACT
Hemoglobin Atlanta, alpha 2 beta 2 75 Leu-Pro (E19), has been found in several members of three generations of a Caucasian family living in metropolitan Atlanta. The abnormal hemoglobin is one of the nine unstable variants in which either a leucyl or an alanyl residue is replaced by a prolyl residue. These substitutions have been observed in the B, E, F, and G helixes of the beta chain and in the H helix of the alpha-chain. Hemoglobin Atlanta heterozygotes are mildly affected by the presence of this unstable hemoglobin.
Subject(s)
Hemoglobins, Abnormal/analysis , Alanine , Amino Acids/analysis , Female , Georgia , Heinz Bodies , Humans , Leucine , Peptide Fragments/analysis , Proline , Protein Conformation , White People
2.
Lancet
; 2(7835): 978, 1973 Oct 27.
Article
in English
| MEDLINE
| ID: mdl-4126611
3.
Ann N Y Acad Sci
; 200: 220-51, 1972 Dec 29.
Article
in English
| MEDLINE
| ID: mdl-4513318
Subject(s)
Coal Mining , Pneumoconiosis/complications , Respiratory Insufficiency/etiology , Accidents, Occupational , Adult , Age Factors , Bronchitis/etiology , Coal/analysis , Disability Evaluation , Dyspnea/etiology , Humans , Legislation, Medical , Male , Middle Aged , Pennsylvania , Pneumoconiosis/diagnostic imaging , Pneumoconiosis/epidemiology , Radiography , Respiratory Function Tests , Respiratory Insufficiency/classification , Smoking/complications , Time Factors , Volatilization
4.
Am J Public Health Nations Health
; 60(3): 441-51, 1970 Mar.
Article
in English
| MEDLINE
| ID: mdl-5461521