Which Tissue Should Be Removed in Upper Blepharoplasty? Analysis and Evaluation of Satisfaction.

BACKGROUND: Due to various options for tissue resection and preoperative markings, many different reports on aesthetics and patient's satisfaction exist. To assess differences among tissue resections and risk factors, we herein analyzed satisfaction levels of patients that underwent upper blepharoplasty. METHODS: A retrospective analysis during the period from January 2006 to June 2013 was conducted by reviewing patient's electronic medical files. All patients underwent medically indicated upper blepharoplasty at our department. We classified patients relating to resected tissues; hence the categories created were skin, skin/muscle, skin/muscle/fat and skin/fat. Furthermore, an evaluation of risk factors according to the patient's number of present medical preconditions ranging from 0 (none) to 4 was performed. Data collection was conducted by reviewing patient's electronic medical files. Moreover, a questionnaire concerning patient's satisfaction was forwarded. RESULTS: No significant differences in patient's satisfaction and complication rates comparing the different groups of tissue resection were noted. However, we found a significantly higher complication rate at a presence of 2 risk factors. In addition, a significantly worse scar outcome and longer recovery periods in patients with 4 risk factors were observed. CONCLUSION: The extent of tissue resection has no statistically quantifiable effect on patient's satisfaction ratings and complications. For this reason, we believe cautious resection of muscle and fat is only indicated if pathologies are present. Moreover, patients with 2 risk factors or more shall be rigorously evaluated preoperatively to avoid complicating events.An abbreviated form of this manuscript was presented at the conjoint 52nd and 45th annual meeting of the Austrian and German Society of Plastic, Aesthetic and Reconstructive Surgery, September 11th-13th 2014 in Munich, Germany.

Correlation between MRI results and intraoperative findings in patients with silicone breast implants.

BACKGROUND: Silicone gel breast implants may silently rupture without detection. This has been the main reason for magnetic resonance imaging (MRI) of the augmented or reconstructed breast. The aim of the present study was to investigate the accuracy of MRI for implant rupture. METHODS: Fifty consecutive patients with 85 silicone gel implants were included in the study. The mean age of the patients was 51 (range 21-72) years, with a mean duration of implantation of 3.8 (range 1-28) years. All patients underwent clinical examination and breast MRI. Intraoperative implant rupture was diagnosed by the operating surgeon. RESULTS: Nineteen of the 50 patients suffered from clinical symptoms. An implant rupture was diagnosed by MRI in 22 of 85 implants (26%). In seven of 17 removed implants (41%), the intraoperative diagnosis corresponded with the positive MRI result. However, only 57% of these patients were symptomatic. Ultrasound imaging of the harvested implants showed signs of interrupted inner layers of the implant despite integrity of the outer shell. By microsurgical separation of the different layers of the implant shell, we were able to reproduce this phenomenon and to produce signs of implant rupture on MRI. CONCLUSION: Our results show that rupture of only the inner layers of the implant shell with integrity of the outer shell leads to a misdiagnosis on MRI. Correlation with clinical symptoms and the specific wishes of the patient should guide the indication for implant removal.

Sural nerve harvesting beyond the popliteal region allows a significant gain of donor nerve graft length.

BACKGROUND: The sural nerve is the nerve most commonly used for peripheral nerve reconstruction. According to requirements for nerve graft length, it is dissected from the retromalleolar up to the popliteal region, where the main root of the sural nerve fibers, the medial sural cutaneous nerve, arises from the tibial nerve. It has been recommended to complete sural nerve harvesting below this area, to avoid damage to the tibial nerve. The aim of this study was to determine whether sural nerve fibers can be isolated from tibial and, more proximal, sciatic nerve fibers to gain more sural nerve graft length. METHODS: The sural nerve was dissected in 30 lower limbs. Anatomical characteristics such as the existence of a union forming the sural nerve, identification of the main root of sural nerve fibers, and the site of origin of the branch(es) forming the sural nerve were noted. Careful nerve preparation in the region of the sural nerve and its main root origin was conducted. RESULTS: In 18 specimens (60 percent), the authors found the classic formation of the sural nerve: the union of the medial sural cutaneous nerve and the peroneal communicating branch. The medial sural cutaneous nerve was the main root of sural nerve fibers in 28 of 30 cases (93 percent) and originated from the tibial nerve. Careful nerve preparation and epineurolysis beyond its anatomical origin allowed isolation and gain of sural nerve graft length of a median of 14 cm. CONCLUSION: In the authors' opinion, this is a feasible method of increasing the quantitative and qualitative outcome of sural nerve harvesting when greater length of sural nerve donor graft is needed for adequate nerve reconstruction.

Breast-conserving therapy for centrally located breast cancer.

OBJECTIVE: To analyze whether breast-conserving therapy (BCT) may be an oncologically safe approach and result in a good cosmesis in patients with centrally located breast cancer (CLBC). SUMMARY BACKGROUND DATA: Only underpowered, retrospective, single-arm studies have suggested that oncoplastic BCT for CLBC may be oncologically safe and may result in a good cosmesis. METHODS: The authors retrospectively analyzed the overall and recurrence-free survival in 1485 patients with breast cancer undergoing BCT comparing CLBC with non-CLBC. Moreover, the authors described 4 different oncoplastic techniques for BCT in patients with CLBC and compared the cosmetic results with simple lumpectomy according to a recently elaborated objective cosmetic evaluation system, the Breast Symmetry Index. RESULTS: Kaplan-Meier curves show no significant difference in a 5-year overall, local, or distant recurrence-free survival between patients with CLBC and non-CLBC after BCT (94% vs. 96%; 100% vs. 98%; 92% vs. 90%; median follow-up, 35.3 months). The cosmetic outcome after oncoplastic BCT compared with simple lumpectomy differed significantly (Breast Symmetry Index: 22 +/- 6%d vs. 44 +/- 12%d; P < 0.05). CONCLUSIONS: The results demonstrate that BCT for CLBC is oncologically safe and that oncoplastic techniques improve cosmesis.

Hypertrophy of the breast: a problem of beauty or health?

BACKGROUND: Despite the complex health burden for women with breast hypertrophy, medical directors of health insurance companies are not convinced that this procedure is of medical benefit for patients. Therefore, coverage of cost by the health insurance companies is no longer guaranteed. The purpose of this study is to evaluate the influence of breast weight on the physical and psychological morbidity of women and to prove the medical necessity of reduction mammaplasty. METHODS: We performed a cohort study of 50 women with various breast sizes, a mean age of 28 years (range 20-40 years), and a body mass index (BMI) <25. Breast weight was measured, the spine was investigated by magnetic resonance imaging (MRI), and a spine score of clinical symptoms was assessed. The Beck Depression Inventory (BDI) was used to evaluate psychological impairment. Pathological findings have been correlated with breast weight, and the risk of developing a morphological or psychological disorder independence of the breast weight was calculated. RESULTS: The incidence of degenerative spine disorders and the extent of depressive symptoms are correlated with increasing breast weight. CONCLUSIONS: The data show that high breast weight has a negative influence on the physical and psychological morbidity of women. This objective evidence in support of the medical necessity of reduction mammaplasty should guide managed care organizations' methods for determining coverage for reduction mammaplasty.

Crucial aspects of smoking in wound healing after breast reduction surgery.

BACKGROUND: The aim of this study was to investigate the influence of cigarette smoking on wound-healing in patients undergoing breast reduction. METHODS: In our prospective study, 50 patients (25 smokers, 25 nonsmokers) scheduled for breast reduction have been evaluated. Urine cotinine levels were measured to analyse perioperative smoking habits. Urine samples were taken preoperatively and on the fourth postoperative day. Cotinine as a metabolite of nicotine allows precise evaluation of nicotine exposure. To assess the progress of woundhealing we classified secreting, instable, inflamed or necrotic wound conditions, which required a dressing after the tenth postoperative day as impaired wound healing. For statistical analysis non-parametrical tests for independent and dependent data were used. RESULTS: Ten of 25 smokers presented impaired wound healing compared to 4 of 25 nonsmokers. The median cotinine level of smokers was 1964 (783/3963)ng/cc preoperatively and 432 (148/1695)ng/cc postoperatively. Nonsmokers had a preoperative cotinine level of 18 (7/37)ng/cc and 15 (4/34)ng/cc postoperatively. Smokers who developed impaired wound-healing showed higher levels of cotinine pre- (2117 ng/cc) and especially postoperatively (485 ng/cc) compared to smokers with regular woundhealing (1614 ng/cc and 389 ng/cc). Both differences in cotinine levels were statistically significant (p=0.03 and p=0.02). CONCLUSIONS: The data of the present study confirm the negative effect of smoking on wound healing in patients undergoing breast reduction.

Vagus nerve stimulation: treatment modality for epilepsy.

Anticonvulsant medication is the golden standard for treatment of epilepsy. For patients who do not benefit sufficiently from anticonvulsants, vagal nerve stimulation using an implantable electrical nerve stimulator may be an option to reduce seizure frequency and intensity, thus improving patients' quality of life. The results of a series of vagus nerve stimulator implantations are described.

Flexor tendon synovitis of the hand as first manifestation of atypical tuberculosis.

We present the case of a 73-year old patient suffering from chronic flexor tendon synovitis of the wrist with carpal tunnel syndrome. He underwent synovectomy and median nerve release. Primary bacteriology was negative. Histology of the excised synovia revelead non-caseating granuloma as typical for sarcoidosis. Further screening for sarcoidosis was negative. Culture of a sample harvested from the poorly healing wound was finally positive for Mycobacterium tuberculosis. Tuberculostatic treatment was started and the wound gradually healed. To the best of our knowledge, this is the first reported case of atypical non-caseating and sarcoidosis-like granulomas of the flexor tendon synovia of the hand as first manifestation of tuberculosis.

Management strategies for peripheral iatrogenic nerve lesions.

For diagnostic or therapeutic reasons, various medical procedures may cause iatrogenic injury of peripheral nerves. The authors treated 82 patients for iatrogenic nerve injury between 1990 and 2000. The main reasons for iatrogenic nerve injury were surgical failure, traction or pressure lesions, hematoma, or inadequate positioning of the patient. The authors performed neurolysis in 67 cases, which included reconstruction by nerve graft in 26 patients and direct coaptation of the nerve in 3 patients. Their postoperative results emphasize the importance of early diagnosis and adequate treatment of iatrogenic peripheral nerve damage for optimal functional recovery. The authors highlight the different causes for iatrogenic injury in this study to alert surgeons as well as other medical specialists to simple strategies for avoiding nerve injury. They also indicate the need for physicians to make themselves familiar with early diagnostic steps for detecting iatrogenic injuries, like electroneurographic studies, and to document physical examinations well, to deal with this problem most effectively.

[Surgical reduction of fat surplus leading to pulmonary embolism]. / Pulmonalembolie nach chirurgischer Fettreduktion.

Surgical reduction of fat surplus is usually performed on healthy individuals and is reported as a safe procedure as it is not associated with a lethal outcome. Due to the anticipation of peri- and postoperative bleeding as a result of the large wound area, which may have a negative influence on the cosmetic result, patients often receive no or only inadequate anticoagulation. We report three cases in which surgical reduction of fat surplus led to sudden collapse and cardiac arrest. In all of our patients, fatal pulmonary embolism was the cause of cardiac arrest. These patients received only inadequate or no anticoagulation. Early postoperative mobilization, elastic stockings and compressive wound-dressing did not prevent pulmonary embolism. In addition to early postoperative mobilization of the patient and even though there is a risk of perioperative bleeding complications, the use of anticoagulation is highly recommended in surgical procedures like abdominoplasty or dermolipectomy. If sudden dyspnea, chest pain, collapse or cardiac arrest occurs after surgical interventions like these, pulmonary embolism should be considered and further diagnostic steps should be initiated.