ABSTRACT
INTRODUCTION: Undernutrition is a predictor of mortality in chronic obstructive pulmonary disease (COPD). The objectives of our study were to assess nutritional intake in COPD and to study its relationship with disease severity. METHODS: A cross-sectional study that included 66 patients followed for COPD. Patients included had a body composition study and a respiratory and nutritional assessment. RESULTS: The mean age of the population was 66±9 years. The lean body mass index (LMI) was reduced in 26.1% of patients. It was significantly associated with the GOLD group (P=0.04) and significantly correlated with the forced expiratory volume in the first second (FEV1) (P=0.02) and the distance covered during the six-minute walk test (TM6) (P=0.01). A significant difference was found between the caloric intakes and the different GOLD groups (P=0.04). Mean intakes of calories (P=0.002; r=0.07), protein (P=0.01; r=0.16), carbohydrates (P=0.02; r=0.2) and iron (P=0.01; r=0.13) were significantly correlated with the TM6 results. Caloric intake was significantly correlated with LMI (P=0.01; r=0.16), body mass index (P=0.04; r=0.12), FEV1 (P=0.04; r=-0.12) and GOLD stage (0.002). Similarly, protein intake was significantly correlated with LMI (P=0.001; r=0.11), body mass index (P=0.02; r=0.16), FEV1(%) (P=0.001; r=-0.16) and GOLD stage (P=0.002). CONCLUSION: Undernutrition in COPD is caused by decreased food intake and increased resting energy expenditure. Adequate intakes of glucose, protein, fibers, vitamins and zinc are associated with improved ventilatory function.
Subject(s)
Nutritional Status , Pulmonary Disease, Chronic Obstructive , Aged , Cross-Sectional Studies , Eating , Forced Expiratory Volume , Humans , Middle Aged , Pulmonary Disease, Chronic Obstructive/epidemiologySubject(s)
Bronchogenic Cyst/diagnosis , Mediastinal Neoplasms/diagnosis , Neurilemmoma/diagnosis , Bronchogenic Cyst/pathology , Diagnosis, Differential , Humans , Male , Mediastinal Neoplasms/pathology , Middle Aged , Neurilemmoma/pathology , Radiography, Thoracic , Smoking/adverse effects , Tomography, X-Ray ComputedSubject(s)
Lung/blood supply , Lung/diagnostic imaging , Pulmonary Veins/diagnostic imaging , Pulmonary Veins/pathology , Varicose Veins/diagnostic imaging , Dilatation, Pathologic , Humans , Lung/pathology , Male , Middle Aged , Radiography, Thoracic , Tomography, X-Ray Computed , Varicose Veins/pathologyABSTRACT
INTRODUCTION: Hydatid cysts may occur in any area of the body, but they usually localize to the liver and the lungs. Primary localization in bone is not common. PRESENTATION OF CASE: The authors report the case of multifocal hydatid disease appeared 3 years after the surgical treatment of a cyst of the hip. The patient presented with cough and chest pain of 2 months duration. Only the lung localization was symptomatic. The thoracic echography, the abdominal and chest scan allowed the diagnosis. DISCUSSION: Hydatid recurrence remain frequent, whatever is the nature of the treatment, surgical or chemical. CONCLUSION: The premature detection of recurrence is of great importance.
Subject(s)
Lymphangioma, Cystic/diagnostic imaging , Mediastinal Neoplasms/diagnostic imaging , Tomography, X-Ray Computed , Adult , Bronchogenic Cyst/diagnosis , Chest Pain/etiology , Diabetes Mellitus, Type 2/complications , Diagnosis, Differential , Female , Humans , Hypertension/complications , Lymphangioma, Cystic/pathology , Lymphangioma, Cystic/surgery , Mediastinal Neoplasms/pathology , Mediastinal Neoplasms/surgery , Teratoma/diagnosisABSTRACT
The aim of this article is to give practicing physicians a practical approach to the treatment of latent and active tuberculosis. Most patients follow TB standard treatment recommended by WHO that depend on category of patient. It is a combination of four essential tuberculosis drugs of the first group: isoniazid, rifampicin, pyrazinamid and ethambutol; in some cases streptomycin can replace ethambutol. This initial phase of intensive treatment is followed by a consolidation phase. Drugs should be administered in the morning on an empty stomach one hour before meals. Treatment of latent tuberculosis (TB) infection is an important component of TB control programs. Preventive treatment can reduce the risk of developing active TB.
Subject(s)
Antitubercular Agents/therapeutic use , Ethambutol/therapeutic use , Isoniazid/therapeutic use , Pyrazinamide/therapeutic use , Rifampin/therapeutic use , Tuberculosis/drug therapy , Drug Therapy, Combination , Humans , Latent Tuberculosis/drug therapy , Practice Guidelines as Topic , Treatment Outcome , Tuberculosis, Pulmonary/drug therapy , World Health OrganizationABSTRACT
The authors report the case of a 20-year-old man in whom pulmonary and bone tuberculosis presented as bilateral pleural thickening without effusion.
Subject(s)
Tuberculosis, Pleural/diagnosis , Granuloma, Plasma Cell/complications , Granuloma, Plasma Cell/diagnosis , Humans , Male , Radiography, Thoracic , Tuberculosis, Osteoarticular/complications , Tuberculosis, Osteoarticular/diagnosis , Tuberculosis, Pleural/complications , Young AdultABSTRACT
BACKGROUND: Since few years, the data describing the chronic obstructive pulmonary disease (COPD) have changed and new concepts have emerged. AIM: To study the clinical characteristics and outcome of patients with COPD in a Tunisian population. METHODS: It is a retrospective study including 150 patients with COPD admitted at the pulmonary department of Charles Nicolle Hospital in Tunis, during a period of ten years. RESULTS: Data from 150 patients hospitalized at the pulmonary department of Charles Nicolle Hospital in Tunis, were analyzed. They were 126 men and 24 women with a mean age of 67 years. Tobacco was the predominant risk factor. Eighty-two (55%) patients were classified GOLD stage IV at diagnosis. The number of exacerbation varied from 1 to 7 with an average higher in patients classified as stage IV (p = 0.007). CONCLUSION: The COPD is pathology of smoking men. Comorbidities and exacerbations prevalence increase according the disease severity. In fact, better knowledge of exacerbations etiologies allows considering better measurement of prevention.
Subject(s)
Hospitalization/statistics & numerical data , Pulmonary Disease, Chronic Obstructive/diagnosis , Adult , Aged , Aged, 80 and over , Disease Progression , Female , Humans , Male , Middle Aged , Pulmonary Disease, Chronic Obstructive/epidemiology , Pulmonary Disease, Chronic Obstructive/therapy , Retrospective Studies , Tunisia/epidemiologyABSTRACT
UNLABELLED: Lung mycosis is rare. Diagnosis and treatment must be done the earliest possible. METHODS: It is about a retrospective study on clinical records including patients hospitalized for lung infection. RESULTS: From 2008 to 2011, 16 patients (13 men and three women, average age 42 years) developed a pulmonary infection. Twelve of our patients had respiratory or extrarespiratory histories. None of our patients had a neutropenia. The diagnoses were lung aspergilloma in four cases, invasive lung aspergillosis in three cases, allergic bronchopulmonary aspergillosis in three cases, mucormycosis in three cases, trichosporonosis in a case, actinomycosis in one case and penicilliosis in one case. An antifungal treatment consisting in amphotericin B or itraconazole was given to four patients and six patients, respectively. Surgery was chosen for six patients. The evolution was good for 12 patients, one presented renal failure, and three patients died.
Subject(s)
Lung Diseases, Fungal/epidemiology , Adult , Aged , Antifungal Agents/therapeutic use , Combined Modality Therapy , Comorbidity , Disease Susceptibility , Female , Humans , Immunocompromised Host , Inpatients/statistics & numerical data , Leukocyte Count , Lung Diseases, Fungal/diagnostic imaging , Lung Diseases, Fungal/drug therapy , Lung Diseases, Fungal/immunology , Lung Diseases, Fungal/surgery , Male , Middle Aged , Neutrophils , Radiography , Retrospective Studies , Treatment Outcome , Young AdultSubject(s)
Bronchial Neoplasms/diagnosis , Neurofibromatoses/diagnosis , Neurofibromatosis 1/diagnosis , Respiratory Distress Syndrome/diagnosis , Bronchial Neoplasms/diagnostic imaging , Bronchial Neoplasms/etiology , Delayed Diagnosis , Disease Progression , Humans , Male , Middle Aged , Neurofibromatoses/diagnostic imaging , Neurofibromatoses/etiology , Neurofibromatosis 1/complications , Neurofibromatosis 1/diagnostic imaging , Radiography, Thoracic , Respiratory Distress Syndrome/diagnostic imaging , Respiratory Distress Syndrome/etiology , Smoking/adverse effects , Tuberculosis, Pulmonary/complications , Tuberculosis, Pulmonary/diagnostic imagingABSTRACT
Bronchopulmonary sequestration is a rare malformation characterized by lung tissue fed by one or several aberrant systemic arteries. The authors present the case of a 35-year-old woman in whom extralobar sequestration was fortuitously detected at the time of persistent pleuropneumopathy. Computed tomography was used in the diagnosis of pulmonary sequestration. The most common and recommended treatment is the surgical removal of the pulmonary sequestration.
Subject(s)
Bronchopulmonary Sequestration/diagnostic imaging , Pleuropneumonia/diagnostic imaging , Tomography, X-Ray Computed , Adult , Anti-Bacterial Agents/therapeutic use , Bronchopulmonary Sequestration/surgery , Bronchoscopy , Chronic Disease , Drug Therapy, Combination , Female , Humans , Incidental Findings , Ofloxacin/therapeutic use , Pleuropneumonia/surgeryABSTRACT
Erythema elevatum diutinum is a rare condition of unknown etiology listed with cutaneous vasculitis or neutrophilic diseases. Medical records and histopathologic slides of 5 patients with erythema elevatum diutinum were studied to better understand the disease. Lesions were clinically characteristic. All biopsy specimens showed leucocytoclastic vasculitis. The most significant finding is the association of erythema elevatum diutinum whith seronegative rheumatoid arthritis.
