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Med J Malaysia ; 74(4): 331-332, 2019 08.
Article in English | MEDLINE | ID: mdl-31424043

ABSTRACT

Osmotic demyelination syndrome results from overly rapid serum sodium correction and is often iatrogenic. We report a 50-year-old hypertensive woman on Indapamide presenting with malaise, dizziness and serum sodium less than 100mmol/l who developed osmotic demyelination syndrome after correction of the hyponatremia. Good neurological recovery was seen after plasmapheresis.


Subject(s)
Demyelinating Diseases/therapy , Hyponatremia/therapy , Plasmapheresis , Saline Solution/adverse effects , Antihypertensive Agents/adverse effects , Biomarkers/blood , Demyelinating Diseases/blood , Demyelinating Diseases/diagnosis , Demyelinating Diseases/etiology , Female , Humans , Hyponatremia/chemically induced , Hyponatremia/complications , Indapamide/adverse effects , Middle Aged , Saline Solution/therapeutic use , Sodium/blood , Syndrome
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