Subject(s)
Hypothalamic Diseases/physiopathology , Hypothalamo-Hypophyseal System/physiopathology , Pituitary Diseases/physiopathology , Thyroid Diseases/physiopathology , Adolescent , Adult , Child , Child, Preschool , Female , Humans , Hypothyroidism/blood , Male , Middle Aged , Thyrotropin/blood , Thyrotropin-Releasing HormoneSubject(s)
3',5'-Cyclic-AMP Phosphodiesterases/antagonists & inhibitors , Metaproterenol/analogs & derivatives , Theophylline/analogs & derivatives , Adrenocorticotropic Hormone/analogs & derivatives , Adrenocorticotropic Hormone/pharmacology , Animals , Drug Combinations , Guinea Pigs , In Vitro Techniques , Intestines/enzymology , Lung/enzymology , Male , Metaproterenol/pharmacology , Muscle, Smooth/enzymology , Muscle, Smooth, Vascular/enzymology , Myocardium/enzymology , Peptide Fragments/pharmacology , Theophylline/pharmacologySubject(s)
Muscles/drug effects , Pyridinium Compounds/pharmacology , Animals , Dogs , Female , Guinea Pigs , Heart/drug effects , Intestines/drug effects , Muscle, Smooth/drug effects , Ranidae , Rats , Receptors, Muscarinic/drug effects , Receptors, Nicotinic/drug effects , Ureter/drug effects , Uterus/drug effectsABSTRACT
In the rat, narcotic doses of Althesin injected intraperitoneally did not modify blood glucose concentration nor plasma insulin concentration. On the contrary a reduction of blood glucose concentration, associated with an increase of plasma insulin concentration was observed when narcotic doses of thiopental and ketamine were. Plasma renin concentration decreased after injection of Althesin and thiopental while increased after injection of ketamine.
Subject(s)
Anesthesia , Blood Glucose/metabolism , Insulin/blood , Renin/blood , Alfaxalone Alfadolone Mixture , Animals , Ketamine , Rats , Thiopental , Time FactorsABSTRACT
In vitro in vivo reproterol showed intense spasmolytic effects upon the trachea and bronchi against various spasm-including agents (histamine, acetylcholine, acetyl-beta-methylcholine, 5-hydroxytryptamine, BaCl2). A comparative study with various drug used in the treatment of asthma (isoprenaline, metaproterenol, salbutamol, clenbuterol, papaverine and atropine) has been conducted.
Subject(s)
Asthma/drug therapy , Bronchi , Metaproterenol/analogs & derivatives , Muscles/drug effects , Theophylline/analogs & derivatives , Trachea , Animals , Atropine/pharmacology , Bronchodilator Agents/pharmacology , Cattle , Dose-Response Relationship, Drug , Drug Combinations , Guinea Pigs , Male , Metaproterenol/pharmacology , Papaverine/pharmacology , Theophylline/pharmacologySubject(s)
Cholestasis/physiopathology , Adenosine Diphosphate/pharmacology , Alfaxalone Alfadolone Mixture/pharmacology , Animals , Bilirubin/blood , Blood Coagulation Disorders/etiology , Blood Platelets/drug effects , Brain/drug effects , Cytochrome P-450 Enzyme System/biosynthesis , L-Lactate Dehydrogenase/blood , Liver/drug effects , Liver/metabolism , Mice , Motor Activity/drug effects , Pentylenetetrazole/pharmacology , Phenobarbital/pharmacology , Rabbits , Rats , Transaminases/bloodABSTRACT
The occlusion of bile duct reduced the microsomal cytochrome P-450 activity in the liver of rats. However, the effects of the inducer drug, phenobarbital, were not abolished.