ABSTRACT
In the rat, narcotic doses of Althesin injected intraperitoneally did not modify blood glucose concentration nor plasma insulin concentration. On the contrary a reduction of blood glucose concentration, associated with an increase of plasma insulin concentration was observed when narcotic doses of thiopental and ketamine were. Plasma renin concentration decreased after injection of Althesin and thiopental while increased after injection of ketamine.
Subject(s)
Anesthesia , Blood Glucose/metabolism , Insulin/blood , Renin/blood , Alfaxalone Alfadolone Mixture , Animals , Ketamine , Rats , Thiopental , Time FactorsABSTRACT
The Authors, thanks to experimental works, have established that piribedil at high concentrations inhibits ADP and thrombin aggregation effect on the rabbit PRP.
Subject(s)
Piperazines/pharmacology , Piribedil/pharmacology , Platelet Aggregation/drug effects , Adenosine Diphosphate/antagonists & inhibitors , Animals , Mice , Rabbits , Thrombin/antagonists & inhibitorsSubject(s)
Cholestasis/physiopathology , Adenosine Diphosphate/pharmacology , Alfaxalone Alfadolone Mixture/pharmacology , Animals , Bilirubin/blood , Blood Coagulation Disorders/etiology , Blood Platelets/drug effects , Brain/drug effects , Cytochrome P-450 Enzyme System/biosynthesis , L-Lactate Dehydrogenase/blood , Liver/drug effects , Liver/metabolism , Mice , Motor Activity/drug effects , Pentylenetetrazole/pharmacology , Phenobarbital/pharmacology , Rabbits , Rats , Transaminases/bloodABSTRACT
Experimental research has shown that pirenzepina possesses interesting inhibiting properties with respect to gastric secretion and the formation of experimentally induced gastric ulcers.
Subject(s)
Benzodiazepinones/pharmacology , Gastric Mucosa/metabolism , Piperazines/pharmacology , Stomach Ulcer/chemically induced , Animals , Atropine/pharmacology , Cardiovascular System/drug effects , Dogs , Dose-Response Relationship, Drug , Female , Gastric Mucosa/drug effects , Kinetics , Male , Mice , Muscle Contraction/drug effects , Pirenzepine , RatsSubject(s)
Metoclopramide/analogs & derivatives , Muscle, Smooth/drug effects , Animals , Bradykinin/antagonists & inhibitors , Dogs , Female , Guinea Pigs , Histamine Antagonists , Intestine, Small/drug effects , Isoproterenol/antagonists & inhibitors , Metoclopramide/pharmacology , Neurotransmitter Agents/antagonists & inhibitors , Prostaglandin Antagonists , Rabbits , Ranidae , Rats , Uterus/drug effectsSubject(s)
Antiemetics/therapeutic use , Gastric Emptying/drug effects , Metoclopramide/analogs & derivatives , Stomach Ulcer/prevention & control , Vomiting/drug therapy , Animals , Central Nervous System/drug effects , Dogs , Female , Male , Metoclopramide/therapeutic use , Mice , Motor Activity/drug effects , RatsABSTRACT
An experimental comparative study has been undertaken to evaluate the action of salmefamol and salbutamol, two sympathomimetic drugs specific for the beta-receptors, on tracheal and bronchial smooth muscles. Salmefamol showed a more intense, longer-lasting beta-adrenergic activity than salbutamol did.
