Real-World Intake of Dietary Sugars Is Associated with Reduced Cortisol Reactivity Following an Acute Physiological Stressor.

There is increasing academic and clinical interest in understanding the nature of the relation between diet and response to stress exposure as a risk factor for mental illness. Cross-species evidence shows that conditions of chronic and acute stress increase the intake of, and preference for, caloric-dense palatable foods, a phenomenon thought to be explained by the mitigating effects of comfort foods on the activity of the stress-response network. It is largely unknown whether and how real-world dietary intake of saturated fat and sugars impacts stress responsivity in humans. Therefore, here we examined whether real-world dietary intake of saturated fat and sugars predicted salivary cortisol reactivity following an acute physiological stressor. Multilevel modelling of four salivary cortisol measures collected up to 65 min after the stressor on 54 participants (18-49 years old) were analyzed using a quadratic growth curve model. Sugar intake significantly predicted a weaker cortisol response following the Cold Pressor Test (CPT) controlling for BMI and gender, revealing an inhibitory effect of caloric-dense diets on cortisol reactivity to stress. As the consumption of sugar rose individuals had lower post-stressor cortisol levels, a smaller rate of increase in cortisol 20 and 35 min after the CPT, a lower cortisol peak, and an overall weaker quadratic effect. These observations add to a growing body of evidence reporting suppressive effects of high-energy foods on stress-associated glucocorticoids reactivity and are consistent with the comfort food hypothesis, where people are seen as motivated to eat palatable foods to alleviate the detrimental repercussions of stressor exposure.

Unconscious Visual Working Memory: A critical review and Bayesian meta-analysis.

The relationship between consciousness and working memory (WM) has been recently debated both at the theoretical and methodological levels (Persuh et al., 2018; Velichkovsky, 2017). While there is behavioral and neural evidence that argues for the existence of unconscious WM, several methodological concerns have been raised, rendering this issue highly controversial. To address the robustness of the previous findings, here we adopt a meta-analytic approach to estimate the effect size and heterogeneity of the previously reported unconscious WM results, also including unpublished results. We used meta-regression to isolate relevant experimental variables, in particular, consciousness manipulation and the WM paradigm to identify the source of the heterogeneity in the reported effect size of the unconscious WM. Our meta-analysis supports the existence of the unconscious WM effect and critically reveals several experimental variables that contribute to relevant heterogeneity. Our analysis clarifies several theoretical and methodological issues. We recommend that future studies explicitly operationalize the definition of consciousness, standardize the methodology and systematically explore the role of critical variables for the unconscious WM effect.