Subject(s)
Alzheimer Disease/complications , Drug Development/methods , Psychomotor Agitation/drug therapy , Antidepressive Agents/administration & dosage , Antidepressive Agents/adverse effects , Antipsychotic Agents/administration & dosage , Antipsychotic Agents/adverse effects , Benzodiazepines/administration & dosage , Benzodiazepines/adverse effects , Biomarkers/blood , Biomarkers/cerebrospinal fluid , Consensus , Humans , Psychomotor Agitation/diagnosis , Psychomotor Agitation/etiology , Randomized Controlled Trials as TopicABSTRACT
This paper presents Petri net models of buffers and a methodology by which buffers can be included in a system without introducing deadlocks or overflows. The context is automated manufacturing. The buffers and models are classified as random order or order preserved (first-in-first-out or last-in-first-out), single-input-single-output or multiple-input-multiple-output, part type and/or space distinguishable or indistinguishable, and bounded or safe. Theoretical results for the development of Petri net models which include buffer modules are developed. This theory provides the conditions under which the system properties of boundedness, liveness, and reversibility are preserved. The results are illustrated through two manufacturing system examples: a multiple machine and multiple buffer production line and an automatic storage and retrieval system in the context of flexible manufacturing.
