1.
Recenti Prog Med
; 98(11): 569-73, 2007 Nov.
Article
in Italian
| MEDLINE
| ID: mdl-18044408
ABSTRACT
In the last years hepatology has known remarkable improvement to understanding the mechanisms involved in familial intrahepatic cholestasis. The role of genetic anomalies is very important. Identification of genes involved in familial intrahepatic cholestasis has proven to be an important strategy to unravel the processes of bile acid synthesis and bile salt transport. The complexity of the mechanisms of bile flow clearly suggests that many more genetic abnormalities have yet to be identified.