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Diabetes Res Clin Pract
; 159: 107661, 2020 Jan.
Article
in English
| MEDLINE
| ID: mdl-30880091
ABSTRACT
Clinical studies showed that dextran sulfate sodium (DSS) alleviates stroke, diabetic retinopathy and hypercholesterolemia, yet its mechanism of action was unrevealed. This study show that DSS reduces hyperglycemia, plasma insulin and enhances glucose utilization by attenuating ROS production, suggesting a novel therapeutic use of DSS in diabetes and its complication.