[Wound infection in the surgical treatment of children with congenital cleft palate]. / Ranevaia infektsiia pri khirurgicheskom lechenii detei s vrozhdennoi rasshchelinoi neba.

Clinico-microbiologic examinations of 153 children with cleft palate aged 2 to 9 were carried out. Two groups of patients with different pattern of operative wound healing after uranoplasty were singled out: 110 ones with primary healing and 13 ones with infectious inflammations of the wound. The incidence of S. aureus carriership on the palatal mucosa before surgery was higher among patients who developed postoperative inflammations. On day 3 after the operation gram-negative bacilli were isolated from the majority of patients with postoperative wound inflammations coursing in the presence of marked dysbacteriosis as against patients in whom the wounds healed by primary intention. The authors suggest a method for wound infection prevention in uranoplasty, consisting in irrigation of the operative wound with acilact (a biopreparation) suspension and shortening of antibiotic prevention course to just 48-72 h; the efficacy of this method was confirmed by a reduction of the incidence of postoperative complications. Normal microflora representatives predominated in the microbiocenosis of the operative wound on days 3 and 10-12 after uranoplasty.