[Soybean bacteriological culture media and prospects for their use in clinical bacteriology]. / Soevye bakteriologicheskie pitatel'nye sredy i perspektivy ikh ispol'zovaniia v klinicheskoi bakteriologii.

Agar bacteriological nutrient media are suggested, based on soybean extract subjected to enzymatic hydrolysis and lyophilized native. The growth of test strains, number of grown colonies and their size were virtually the same as after inoculation of these strains in control nutrient media. Soybean salt medium with yolk suspension was tried with good results as elective medium for isolation of staphylococci from clinical material. Commercial manufacture of these media mainly from native soybean extract is proposed.

[The paradoxes of staphylococcal infection in dentistry]. / Paradoksy stafilokokkovoi infektsii v stomatologii.

Study of the role of staphylococcal infection in pyoinflammatory complications of mandibular injuries showed that immunization of this category of patients with staphylococcal antitoxin simultaneously with antibiotic therapy leads to a significant increase in the blood level of anti-alpha-toxin. The latter has a positive impact on the clinical course of disease and staphylococcal contamination of involved site and oronasal mucosa.

[The patient's own staphylococcal strains of nasal origin as potential causative agents of inflammatory processes in the maxillofacial area]. / Autoshtammy stafilokokkov nazal'nogo proiskhozhdeniia kak potentsial'nye vozbuditeli vospalitel'nykh protsessov cheliustno-litsevoi oblasti.

Buccal mucosa was microbiologically examined in 1169 stomatologic patients, nasal mucosa (anterior segments) in 1035, and foci of involvement in 494 patients. High staphylococcal contamination of the nasal mucosa of stomatologic patients was found to be a stable parameter not depending on patients' age, sex, disease entity, or season. The intensity of oral contamination depends on a number of factors, such as age, sex, disease entity, and season, as well as the degree of nasal cavity contamination with staphylococci. These factors' effects appear to be realized via salivary antibacterial properties. Phage typing results and antibioticograms of the defected staphylococci indicate that the majority of these microorganisms contaminating the oral cavity originate from the nasal cavity. A conclusion is made about advisability of nasal cavity treatment with antistaphylococcal agents to prevent pyoinflammatory complications after surgical interventions, as well as in patients with maxillofacial injuries.

[Protease as an immune response enhancer in immunization with an adsorbed staphylococcal anatoxin]. / Proteaza kak usilitel' immunogo otveta pri immunizatsii adsorbirovannym stafilokokkovym anatoksinom.

The injection of trypsin into rabbits immunized with adsorbed staphylococcal toxoid was found to have a potentiating effect on the immune response of the body, which was manifested by a considerable increase in the specific antibody titer and by the activation of nonspecific systemic protective factors. The intensity of antistaphylococcal immunity achieved by the moment of challenge (on day 23 of the experiment) in the animals ensured the resistance of the rabbits to staphylococcal test infection. The injection of trielin, a proteolysis inhibiting agent, simultaneously with the immunization of rabbits with adsorbed staphylococcal toxoid produced no such effect.

[Effect of streptomycin on experimental indices of immunity and nonspecific protection]. / Vliianie streptomitsina na pokazateli immuniteta i nespetsificheskoi zashchity v éksperimente.

It was found that streptomycin administered to rabbits immunized with adsorbed staphylococcal anatoxin did not induce any decrease in the antitoxic antistaphylococcal immunity or suppress the activity of the nonspecific protection factors. The level of the antistaphyloccal immunity observed in the experiments provided the rabbit resistance to experimental staphylococcal infection and prevented its generalization.