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1.
Bull Soc Pathol Exot ; 108(1): 32-5, 2015 Feb.
Article in French | MEDLINE | ID: mdl-25516291

ABSTRACT

Congenital heart diseases are one of the major cardiovascular diseases in developing countries. Most prevalence studies were based on clinical examination of children with echocardiographic confirmation of suspected cases and underestimate its prevalence. The objective of this study was to investigate the prevalence of congenital heart disease in "daara" (Koranic schools) in the city of Dakar and its suburbs on the basis of clinical examination and Doppler echocardiography in school children. This cross-sectional survey was carried out from 9(th) August to 24(th) December 2011, and included a population of 2019 school children aged 5 to 18 years in 16 selected "daaras" under the Academic Inspectorate of Dakar and its suburbs. Anamnestic, clinical and echocardiographic data were recorded in a validated questionnaire. A p < 0.05 was considered to be statistically significant in bivariate analysis. 2 019 school children were included out of which 60.1% were male (sex-ratio: 0.66). The average age was 9.7 years (± 3.3 years). 18 cases of congenital heart diseases were detected being a prevalence of 8.9 per 1 000 (95 % CI: 1.8 to 7.9). This included 6 cases of inter-atrial septal aneurysm, 5 cases of peri-membranous ventricular septal defects, 4 cases of patent ductusarteriosus and 3 cases of tetralogy of Fallot. Factors correlated with the presence of congenital heart disease were ageless than 8 (p <0.001) and residence in the suburbs of Dakar (p <0.001). We also detected 10 cases of rheumatic valvular disease, a prevalence of 4.9 per 1 000 (95% CI: 2.4 to 9.1). Our study shows a high prevalence of congenital heart diseases, which is almost identical to the WHO estimates and that ultrasound screening is more sensitive than clinical screening. Reducing the prevalence of these diseases requires implementation of appropriate policies, focusing on awareness and early detection.


Subject(s)
Heart Defects, Congenital/epidemiology , Schools/statistics & numerical data , Adolescent , Child , Child, Preschool , Cross-Sectional Studies , Echocardiography, Doppler , Female , Heart Defects, Congenital/diagnostic imaging , Humans , Islam , Male , Mass Screening , Prevalence , Senegal/epidemiology
2.
Ann Cardiol Angeiol (Paris) ; 61(4): 287-9, 2012 Aug.
Article in French | MEDLINE | ID: mdl-21665188

ABSTRACT

We report the case of Conn's adenoma in a 36-year-old woman, revealed by low extremities weakness. The patient had hypertension at 170/90 mmHg. Her initial potassium level was low i.e., 1.5 mmol/L. The diagnosis, confirmed by hormonal investigation, showed an elevation of plasma aldosterone and lower plasma renin activity. Abdominal MRI revealed a lesion in left adrenal gland, measuring 1.8 cm in diameter and taking contrast in periphery, compatible with an adrenal adenoma. The patient underwent a left laparoscopic adrenalectomy and microscopic examination confirmed the diagnosis. The postoperative course was uneventful with normalization of serum potassium level and blood pressure.


Subject(s)
Adrenal Cortex Neoplasms/complications , Adrenal Cortex Neoplasms/diagnosis , Adrenocortical Adenoma/complications , Adrenocortical Adenoma/diagnosis , Paraplegia/etiology , Adrenal Cortex Neoplasms/blood , Adrenal Cortex Neoplasms/surgery , Adrenalectomy , Adrenocortical Adenoma/blood , Adrenocortical Adenoma/surgery , Adult , Aldosterone/blood , Biomarkers/blood , Female , Humans , Hypertension/etiology , Magnetic Resonance Imaging , Paraplegia/surgery , Treatment Outcome
3.
Ann Cardiol Angeiol (Paris) ; 60(2): 67-70, 2011 Apr.
Article in French | MEDLINE | ID: mdl-20708727

ABSTRACT

INTRODUCTION: Diabetes is a major risk factor for coronary artery disease witch may develop insidiously. Several non-invasive methods are used to detect silent myocardial ischaemia, especially in diabetic patients at high cardiovascular risk. We project to screen, by dobutamine stress echocardiography, silent myocardial ischaemia in type 2 diabetics in Senegal. METHODOLOGY: We randomly recruited in hospital in Senegal type 2 diabetics aged at least 40 years and a dobutamine stress echocardiography was performed in those selected according to the French Society of Cardiology and the French Language Association for the Study of Diabetes and Metabolic Diseases. RESULTS: Dobutamine stress echocardiography was performed in 79 diabetics at high cardiovascular risk, including 56 women. The average age was 58.8±11.8 years. The exam was positive in 67.1% of cases (53/79), with a predominance of motion abnormalities in anterior territory (83%). Cardiovascular risk factors associated with positivity of test were microalbuminuria (p=0.0001), inactivity (p=0.0001), dyslipidemia (p=0.0002), arterial hypertension (p=0.001), smoking (0.003) and male sex (p=0.004). CONCLUSION: In Africa, dobutamine stress echocardiography has the advantage of its accessibility and its feasibility. Early detection of silent myocardial ischaemia in diabetics at high risk could optimize their care.


Subject(s)
Cardiotonic Agents , Diabetes Complications/diagnostic imaging , Diabetes Mellitus, Type 2/complications , Dobutamine , Echocardiography, Stress , Mass Screening , Myocardial Ischemia/diagnostic imaging , Adult , Aged , Albuminuria/complications , Coronary Artery Disease/diagnostic imaging , Dyslipidemias/complications , Feasibility Studies , Female , Humans , Hypertension/complications , Life Style , Male , Middle Aged , Myocardial Ischemia/complications , Predictive Value of Tests , Prognosis , Retrospective Studies , Risk Assessment , Risk Factors , Senegal , Sensitivity and Specificity , Sex Distribution , Smoking/adverse effects
4.
Ann Cardiol Angeiol (Paris) ; 59(1): 40-3, 2010 Feb.
Article in French | MEDLINE | ID: mdl-19962690

ABSTRACT

Right atrial myxoma is a heart benignant tumor characterized by an important clinical polymorphism. We report a case of a 30-year-old female with a diagnosis of a big right atrial myxoma. The diagnosis has been done by transthoracic echocardiography which showed an important tumorous mass in the right atrium. It was moving, inhomogeneous and takes over the whole of right atrium cavity. The surgical excision of the tumor has been done under extracorporal circulation. The patient died after a second intervention for tricuspid failure.


Subject(s)
Heart Atria , Heart Neoplasms/diagnosis , Myxoma/diagnosis , Ventricular Dysfunction, Right/diagnosis , Ventricular Dysfunction, Right/etiology , Adult , Echocardiography , Electrocardiography , Fatal Outcome , Female , Heart Atria/pathology , Heart Atria/surgery , Heart Neoplasms/pathology , Heart Neoplasms/surgery , Humans , Myxoma/pathology , Myxoma/surgery , Postoperative Complications/diagnosis , Postoperative Complications/surgery , Reoperation , Tricuspid Valve Insufficiency/diagnosis , Tricuspid Valve Insufficiency/pathology , Tricuspid Valve Insufficiency/surgery , Ventricular Dysfunction, Right/pathology , Ventricular Dysfunction, Right/surgery
5.
Dakar Med ; 52(3): 175-9, 2007.
Article in French | MEDLINE | ID: mdl-19097398

ABSTRACT

INTRODUCTION: Pulmonary hypertension (PH) is a complication of autoimmune diseases which worsen the prognosis. In Senegal, a few cases of PH have been previously reported in patients with systemic sclerosis. CASE REPORTS: We report two cases of patients with PH that revealed autoimmune diseases (Sharp' syndrome and Sjögren syndrome). Epidemiological, clinical, evolutive and laboratory data were analyzed. Evolution of disease was favourable for one patient and fatal for the other. CONCLUSION: These two cases show necessity of early diagnosis of systemic diseases in our countries. PH should be screened in each patient with autoimmune disease before installation of irreversible pulmonary arterial lesions that respond to treatment. New therapy used in idiopathic PH are not yet accessible for our patients.


Subject(s)
Hypertension, Pulmonary/etiology , Mixed Connective Tissue Disease/diagnosis , Sjogren's Syndrome/diagnosis , Adult , Female , Humans , Middle Aged , Mixed Connective Tissue Disease/complications , Sjogren's Syndrome/complications
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